Standard name Systematic name Name description Description
GRX5 YPL059W Glutathione-dependent oxidoreductase Glutathione-dependent oxidoreductase; mitochondrial matrix protein involved at an early step in the biogenesis of iron-sulfur centers along with Bol1p; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p
Visualize the interactome of GRX5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.893 0.860 0.969
Nucleolus 0.064 NaN NaN
Vac/Vac Memb 0.180 0.157 0.073
Nuc Periphery NaN NaN 0.062

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 6260

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GRX5 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0482 (glutathione oxidoreductase), r_0484 (glutathione peroxidase, mitochondria)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 3 2 1 Two-hybrid, Two-hybrid, Co-localization
SSC1 YJR045C Hsp70 family ATPase physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 2 1 2 Two-hybrid, Two-hybrid
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSQ1 YLR369W Mitochondrial hsp70-type molecular chaperone physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HCM1 YCR065W Forkhead transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Phenotypic Suppression
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Synthetic Growth Defect
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSQ1 YLR369W Mitochondrial hsp70-type molecular chaperone genetic 1 1 1 Dosage Rescue
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
KDX1 YKL161C Protein kinase genetic 1 1 1 Phenotypic Enhancement
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
ISA2 YPR067W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Dosage Rescue
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Lethality
NRT1 YOR071C High-affinity nicotinamide riboside transporter genetic 1 1 1 Positive Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Negative Genetic
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Positive Genetic
HXT11 YOL156W Hexose transporter genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Phenotypic Suppression
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Growth Defect
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients physical 1 1 1 Affinity Capture-MS
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Synthetic Rescue
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family physical 1 1 1 PCA
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Synthetic Rescue
BOL1 YAL044W-A Mitochondrial matrix protein involved in Fe-S cluster biogenesis physical 1 1 1 Affinity Capture-MS
AMD2 YDR242W Putative amidase genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality