Standard name Systematic name Name description Description
ISA2 YPR067W Protein required for maturation of mitochondrial [4Fe-4S] proteins Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations
Visualize the interactome of ISA2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.879 0.899 0.747
Nuc Periphery 0.081 NaN NaN
Nucleolus 0.054 NaN NaN
Peroxisome 0.056 NaN 0.057
Vac/Vac Memb 0.137 0.132 0.103
Cell Periphery NaN 0.054 0.057
Golgi NaN 0.061 0.316
Endosome NaN NaN 0.063

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 1560

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ISA2 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
IBA57 YJR122W Protein involved in incorporating iron-sulfur clusters into proteins physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 1 1 1 Affinity Capture-MS
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Dosage Rescue
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
TAZ1 YPR140W Lyso-phosphatidylcholine acyltransferase genetic 1 1 1 Synthetic Growth Defect
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Dosage Rescue
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Biochemical Activity
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Synthetic Growth Defect
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
GRX5 YPL059W Glutathione-dependent oxidoreductase genetic 1 1 1 Dosage Rescue
IRE1 YHR079C Serine-threonine kinase and endoribonuclease physical 1 1 1 Biochemical Activity
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients physical 1 1 1 Affinity Capture-MS
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family genetic 1 1 1 Dosage Rescue
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality