Standard name Systematic name Name description Description
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
Visualize the interactome of SPC97
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 62

CYCLoPs localization & abundance

WT1 WT2 WT3
Budsite 0.053 NaN NaN
Mito 0.057 0.062 NaN
Nucleolus 0.278 0.206 0.065
SpindlePole 0.844 0.853 0.955
Endosome NaN 0.050 NaN

GFP localization & abundance

GFP localization GFP abundance
spindle pole 2230

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SPC97 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 25 6 17 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, FRET, FRET, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, FRET, Affinity Capture-MS
TUB4 YLR212C Gamma-tubulin physical 25 5 16 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, FRET, FRET, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 12 5 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, FRET, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 9 6 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Co-purification, Co-purification, FRET, FRET, Affinity Capture-MS, Affinity Capture-MS
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 5 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 3 2 2 Dosage Rescue, Dosage Rescue, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Negative Genetic, Dosage Lethality
KAR1 YNL188W Protein involved in karyogamy and spindle pole body duplication physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 1 Negative Genetic, Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Negative Genetic, Positive Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Positive Genetic
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
SAP1 YER047C Putative ATPase of the AAA family genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Positive Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Affinity Capture-MS
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Positive Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Dosage Rescue
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family physical 1 1 1 Affinity Capture-Western
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
TUB1 YML085C Alpha-tubulin physical 1 1 1 Co-localization
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Synthetic Lethality
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
YAL063C-A YAL063C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 1 1 1 Negative Genetic
YER186C YER186C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Negative Genetic
YKR075C YKR075C Protein of unknown function genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
UNG1 YML021C Uracil-DNA glycosylase genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSO1 YPL232W Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
CYM1 YDR430C Lysine-specific metalloprotease of the pitrilysin family genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Affinity Capture-Western
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Synthetic Rescue
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Positive Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Positive Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor genetic 1 1 1 Dosage Rescue
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Affinity Capture-MS
ALF1 YNL148C Alpha-tubulin folding protein genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Affinity Capture-MS
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Affinity Capture-MS
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication physical 1 1 1 Affinity Capture-MS
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Negative Genetic
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication physical 1 1 1 Affinity Capture-MS
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 Two-hybrid
HCH1 YNL281W Heat shock protein regulator genetic 1 1 1 Negative Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
NBP1 YLR457C Spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
HOT13 YKL084W Zinc-binding mitochondrial intermembrane space (IMS) protein genetic 1 1 1 Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Positive Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
EXG2 YDR261C Exo-1,3-beta-glucanase genetic 1 1 1 Negative Genetic
NDJ1 YOL104C Protein that regulates meiotic SPB cohesion and telomere clustering physical 1 1 1 Affinity Capture-MS
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
DSE4 YNR067C Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Negative Genetic
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function genetic 1 1 1 Negative Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL6A YML073C Ribosomal 60S subunit protein L6A genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
RPL15B YMR121C Ribosomal 60S subunit protein L15B genetic 1 1 1 Negative Genetic
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Negative Genetic
CTR86 YCR054C Essential protein of unknown function genetic 1 1 1 Positive Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
MIN4 YML007C-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic