Standard name Systematic name Name description Description
SSO1 YPL232W Plasma membrane t-SNARE Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p; SSO1 has a paralog, SSO2, that arose from the whole genome duplication
Visualize the interactome of SSO1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 14

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.600 0.626 0.528
Endosome 0.119 0.189 0.146
Mito 0.185 NaN 0.203
Vac/Vac Memb 0.133 0.263 0.114
SpindlePole NaN NaN 0.098

GFP localization & abundance

GFP localization GFP abundance
lipid particle 450

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SSO1 0 5 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion physical 19 5 13 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, PCA
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 10 3 9 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, PCA, Reconstituted Complex
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) physical 8 4 8 Affinity Capture-Western, Affinity Capture-Western, FRET, FRET, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) physical 8 5 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-fractionation
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 8 4 7 Dosage Rescue, Synthetic Rescue, Dosage Lethality, Dosage Rescue, Negative Genetic, Dosage Rescue, Dosage Rescue, Negative Genetic
SEC22 YLR268W R-SNARE protein physical 7 3 6 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, PCA
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery physical 7 4 3 Affinity Capture-Western, Affinity Capture-Western, PCA, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, PCA
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 4 3 3 FRET, Two-hybrid, Affinity Capture-Western, Two-hybrid
SLT2 YHR030C Serine/threonine MAP kinase genetic 4 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex physical 4 2 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 3 3 3 Dosage Rescue, Synthetic Rescue, Negative Genetic
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 3 3 3 Synthetic Growth Defect, Dosage Rescue, Negative Genetic
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 3 1 3 Dosage Rescue, Dosage Rescue, Dosage Rescue
DDI1 YER143W Aspartic-type endopeptidase physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Dosage Growth Defect, Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 2 2 2 Phenotypic Suppression, Negative Genetic
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 2 2 2 Dosage Rescue, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 2 2 2 Synthetic Lethality, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 2 Negative Genetic, Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 2 1 2 Biochemical Activity, Biochemical Activity
VAM7 YGL212W Vacuolar SNARE protein physical 2 1 2 Two-hybrid, Two-hybrid
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Negative Genetic, Negative Genetic
OSH3 YHR073W Member of an oxysterol-binding protein family physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I physical 1 1 1 Affinity Capture-MS
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Affinity Capture-Western
BOI2 YER114C Protein involved in polar growth genetic 1 1 1 Dosage Rescue
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Two-hybrid
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
ATG18 YFR021W Phosphoinositide binding protein physical 1 1 1 Affinity Capture-MS
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Phenotypic Enhancement
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 PCA
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Affinity Capture-Western
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC17 YBL050W Alpha-SNAP cochaperone physical 1 1 1 Reconstituted Complex
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Dosage Lethality
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Reconstituted Complex
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Dosage Rescue
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Dosage Rescue
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 Affinity Capture-Western
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Dosage Lethality
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Two-hybrid
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Two-hybrid
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Two-hybrid
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
DDI1 YER143W Aspartic-type endopeptidase genetic 1 1 1 Synthetic Rescue
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Affinity Capture-MS
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Two-hybrid
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Two-hybrid
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Dosage Rescue
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex genetic 1 1 1 Dosage Rescue
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Two-hybrid
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
TLG2 YOL018C Syntaxin-like t-SNARE physical 1 1 1 Affinity Capture-Western
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Synthetic Growth Defect
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
STE4 YOR212W G protein beta subunit physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex physical 1 1 1 Two-hybrid
TMA17 YDL110C Regulatory gamma subunit of fatty acid synthase (FAS) physical 1 1 1 Two-hybrid
VAB2 YEL005C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease physical 1 1 1 Affinity Capture-MS
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE physical 1 1 1 Reconstituted Complex
ZIP2 YGL249W Meiosis-specific protein physical 1 1 1 Affinity Capture-MS
SSO1 YPL232W Plasma membrane t-SNARE physical 1 1 1 PCA
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Dosage Rescue
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Phenotypic Enhancement
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex genetic 1 1 1 Phenotypic Suppression
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Positive Genetic
MRF1 YGL143C Mitochondrial translation release factor genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
KAR5 YMR065W Protein required for nuclear membrane fusion during karyogamy physical 1 1 1 Two-hybrid
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family physical 1 1 1 Two-hybrid
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 1 1 1 Two-hybrid
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 1 1 1 Two-hybrid