Standard name Systematic name Name description Description
ROG3 YFR022W Alpha-arrestin involved in ubiquitin-dependent endocytosis Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication
Visualize the interactome of ROG3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ROG3 2 0 0 3 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 7 3 4 Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 3 2 2 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase physical 2 2 2 Biochemical Activity, Two-hybrid
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 2 1 Phenotypic Enhancement, Dosage Rescue
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 2 1 1 Reconstituted Complex, Reconstituted Complex
GRE3 YHR104W Aldose reductase genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Two-hybrid
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein physical 1 1 1 Reconstituted Complex
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Biochemical Activity
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Rescue
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Two-hybrid
RIM11 YMR139W Protein kinase genetic 1 1 1 Synthetic Rescue
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 Affinity Capture-MS
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
STE2 YFL026W Receptor for alpha-factor pheromone physical 1 1 1 Reconstituted Complex
STE2 YFL026W Receptor for alpha-factor pheromone genetic 1 1 1 Phenotypic Enhancement
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Co-purification
YPT1 YFL038C Rab family GTPase physical 1 1 1 Reconstituted Complex
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Positive Genetic
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
VPS62 YGR141W Vacuolar protein sorting (VPS) protein genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell genetic 1 1 1 Phenotypic Enhancement
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic