STE2 |
YFL026W |
Receptor for alpha-factor pheromone |
physical |
11 |
5 |
11 |
Affinity Capture-Western, FRET, Affinity Capture-Western, Reconstituted Complex, FRET, PCA, PCA, Reconstituted Complex, FRET, PCA, Co-purification |
GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
physical |
5 |
4 |
4 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, PCA, FRET |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
STE4 |
YOR212W |
G protein beta subunit |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Dosage Growth Defect |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
MF(ALPHA)1 |
YPL187W |
Mating pheromone alpha-factor, made by alpha cells |
physical |
3 |
3 |
2 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, northern blot evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Dosage Rescue |
GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Dosage Rescue |
STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
genetic |
2 |
2 |
2 |
Dosage Rescue, Phenotypic Suppression |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
STE4 |
YOR212W |
G protein beta subunit |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
SIR3 |
YLR442C |
Silencing protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCM1 |
YMR043W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PUT3 |
YKL015W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
regulation |
1 |
1 |
1 |
northern blot evidence |
MATALPHA2 |
YCR039C |
Homeobox-domain protein |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Co-localization |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Dosage Lethality |
AFR1 |
YDR085C |
Protein required for pheromone-induced projection (shmoo) formation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
PCA |
STE3 |
YKL178C |
Receptor for a factor pheromone |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MATALPHA2 |
YCR039C |
Homeobox-domain protein |
physical |
1 |
1 |
1 |
Co-localization |
ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ACB1 |
YGR037C |
Acyl-CoA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MF(ALPHA)2 |
YGL089C |
Mating pheromone alpha-factor, made by alpha cells |
physical |
1 |
1 |
1 |
Co-purification |
LSB6 |
YJL100W |
Type II phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GUP2 |
YPL189W |
Probable membrane protein |
physical |
1 |
1 |
1 |
PCA |
PPN2 |
YNL217W |
Zn2+-dependent endopolyphosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |