Standard name Systematic name Name description Description
STE7 YDL159W Signal transducing MAP kinase kinase Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway
Visualize the interactome of STE7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.996 0.97 0.985

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 672

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
STE7 0 0 0 10 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 23 7 19 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, FRET, FRET, Biochemical Activity, Affinity Capture-MS, PCA, PCA, Two-hybrid, Biochemical Activity
STE5 YDR103W Pheromone-responsive MAPK scaffold protein physical 21 7 17 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, FRET, FRET, Reconstituted Complex, Far Western, PCA, Reconstituted Complex, Two-hybrid, Two-hybrid
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 16 8 13 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, FRET, Biochemical Activity, Affinity Capture-MS, PCA, PCA
STE11 YLR362W Signal transducing MEK kinase physical 6 4 5 Affinity Capture-Western, Biochemical Activity, FRET, FRET, Two-hybrid, Two-hybrid
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 3 3 3 Synthetic Rescue, Dosage Rescue, Phenotypic Enhancement
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
STE4 YOR212W G protein beta subunit genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
STE7 YDL159W Signal transducing MAP kinase kinase physical 2 2 2 FRET, Two-hybrid
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions physical 2 2 1 Affinity Capture-Western, Biochemical Activity
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STE11 YLR362W Signal transducing MEK kinase regulation 1 1 1 tryptic phosphopeptide mapping assay evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Phenotypic Suppression
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Phenotypic Suppression
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Affinity Capture-Western
HHF1 YBR009C Histone H4 physical 1 1 1 Biochemical Activity
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP physical 1 1 1 Reconstituted Complex
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Reconstituted Complex
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-RNA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Phenotypic Suppression
SPH1 YLR313C Protein involved in shmoo formation and bipolar bud site selection physical 1 1 1 Two-hybrid
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Phenotypic Suppression
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Two-hybrid
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Phenotypic Suppression
GPA1 YHR005C Subunit of G protein involved in pheromone response genetic 1 1 1 Synthetic Rescue
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 PCA
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Phenotypic Suppression
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay physical 1 1 1 Affinity Capture-MS
SNO4 YMR322C Possible chaperone and cysteine protease physical 1 1 1 PCA
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
STE2 YFL026W Receptor for alpha-factor pheromone genetic 1 1 1 Phenotypic Suppression
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Rescue
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Dosage Growth Defect
SPA2 YLL021W Component of the polarisome physical 1 1 1 Two-hybrid
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Dosage Rescue
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Phenotypic Enhancement
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MIG2 YGL209W Zinc finger transcriptional repressor physical 1 1 1 Two-hybrid
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Biochemical Activity
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Phenotypic Suppression
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Reconstituted Complex
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Synthetic Rescue
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 1 1 1 Synthetic Lethality
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
IMA1 YGR287C Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) physical 1 1 1 Reconstituted Complex