Standard name Systematic name Name description Description
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p; required for stability of the Dam1p-Duo1p complex
Visualize the interactome of PSE1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.852 0.956 0.717
Vac/Vac Memb 0.148 NaN 0.232
ER NaN NaN 0.057

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 15500

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PSE1 2 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 12 5 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, FRET, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 10 4 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex
GSP1 YLR293C Ran GTPase physical 8 3 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 5 3 4 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 5 3 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 5 3 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex physical 4 4 4 Two-hybrid, FRET, Reconstituted Complex, Affinity Capture-Western
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
KAP95 YLR347C Karyopherin beta physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor physical 4 4 2 Affinity Capture-MS, Co-purification, Affinity Capture-Western, Two-hybrid
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 4 4 2 Affinity Capture-Western, Co-fractionation, Reconstituted Complex, Co-crystal Structure
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 4 1 2 Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 4 4 1 Co-localization, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 3 3 3 Affinity Capture-Western, Affinity Capture-MS, FRET
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 3 3 3 Two-hybrid, Affinity Capture-MS, Reconstituted Complex
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
HHT1 YBR010W Histone H3 physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ELM1 YKL048C Serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SPO12 YHR152W Nucleolar protein of unknown function physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 3 2 Synthetic Lethality, Negative Genetic, Positive Genetic
HHT2 YNL031C Histone H3 physical 3 3 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
HTB1 YDR224C Histone H2B physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SRP1 YNL189W Karyopherin alpha homolog physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
HHF2 YNL030W Histone H4 physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 2 2 2 FRET, Reconstituted Complex
GSP2 YOR185C GTP binding protein (mammalian Ranp homolog) physical 2 2 2 Affinity Capture-MS, Two-hybrid
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
INO4 YOL108C Transcription factor involved in phospholipid synthesis physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MDS3 YGL197W Putative component of the TOR regulatory pathway physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPA2 YLL021W Component of the polarisome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YMR310C YMR310C Putative methyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 2 Positive Genetic, Positive Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 2 1 2 Positive Genetic, Positive Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Positive Genetic, Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 2 Negative Genetic, Negative Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 2 1 2 Negative Genetic, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 2 Negative Genetic, Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 2 1 2 Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Negative Genetic, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 2 Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 2 1 2 Negative Genetic, Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 2 1 2 Negative Genetic, Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 1 2 Negative Genetic, Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 2 1 2 Positive Genetic, Positive Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 2 1 2 Negative Genetic, Negative Genetic
KAP123 YER110C Karyopherin beta genetic 2 2 1 Phenotypic Enhancement, Synthetic Growth Defect
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 2 2 1 Co-localization, Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 1 Co-crystal Structure, Reconstituted Complex
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 2 2 1 FRET, Affinity Capture-Western
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II physical 2 2 1 Reconstituted Complex, Protein-peptide
DSL1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic genetic 2 2 1 Negative Genetic, Positive Genetic
HO YDL227C Site-specific endonuclease physical 2 2 1 Two-hybrid, Reconstituted Complex
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Positive Genetic, Negative Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Synthetic Lethality
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex physical 1 1 1 Two-hybrid
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Positive Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KGD2 YDR148C Dihydrolipoyl transsuccinylase physical 1 1 1 Two-hybrid
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis physical 1 1 1 Reconstituted Complex
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Reconstituted Complex
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits genetic 1 1 1 Dosage Rescue
SOR1 YJR159W Sorbitol dehydrogenase physical 1 1 1 Two-hybrid
WTM2 YOR229W Transcriptional modulator physical 1 1 1 Two-hybrid
SOR2 YDL246C Sorbitol dehydrogenase physical 1 1 1 Two-hybrid
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis physical 1 1 1 Two-hybrid
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-Western
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Two-hybrid
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family physical 1 1 1 Reconstituted Complex
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease physical 1 1 1 Affinity Capture-MS
THO1 YER063W Conserved nuclear RNA-binding protein physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex physical 1 1 1 Affinity Capture-Western
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) physical 1 1 1 Affinity Capture-Western
RDR1 YOR380W Transcriptional repressor involved in regulating multidrug resistance physical 1 1 1 Two-hybrid
YPL088W YPL088W Putative aryl alcohol dehydrogenase physical 1 1 1 Two-hybrid
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit physical 1 1 1 Reconstituted Complex
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Reconstituted Complex
TSR2 YLR435W Protein with a potential role in pre-rRNA processing physical 1 1 1 Reconstituted Complex
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Reconstituted Complex
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Reconstituted Complex
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Reconstituted Complex
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Phenotypic Suppression
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 1 1 1 Positive Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Dosage Rescue
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Positive Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Positive Genetic
YGR018C YGR018C Protein of unknown function genetic 1 1 1 Positive Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
PYP1 YNL010W Sugar alcohol phosphatase genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Dosage Lethality
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Two-hybrid
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Affinity Capture-MS
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 physical 1 1 1 Affinity Capture-MS
NTE1 YML059C Serine esterase physical 1 1 1 Affinity Capture-MS
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Two-hybrid
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
AIM46 YHR199C Protein of unknown function physical 1 1 1 Affinity Capture-MS
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
PAP2 YOL115W Non-canonical poly(A) polymerase physical 1 1 1 Affinity Capture-MS
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 1 1 1 FRET
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-Western
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 1 1 1 FRET
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Phenotypic Suppression
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis physical 1 1 1 Reconstituted Complex
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Growth Defect
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Reconstituted Complex
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin physical 1 1 1 Two-hybrid
ACA1 YER045C ATF/CREB family basic leucine zipper (bZIP) transcription factor physical 1 1 1 Two-hybrid
MND2 YIR025W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Two-hybrid
CSM3 YMR048W Replication fork associated factor physical 1 1 1 Two-hybrid
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Lethality
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Positive Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity physical 1 1 1 Reconstituted Complex
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Dosage Rescue
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 Two-hybrid
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
GSY2 YLR258W Glycogen synthase physical 1 1 1 Affinity Capture-MS
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Positive Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Reconstituted Complex
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 FRET
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase physical 1 1 1 Affinity Capture-MS
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 Reconstituted Complex
APE4 YHR113W Cytoplasmic aspartyl aminopeptidase with possible vacuole function physical 1 1 1 Two-hybrid
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
BER1 YLR412W Protein involved in microtubule-related processes genetic 1 1 1 Negative Genetic
LDS2 YOL047C Protein Involved in spore wall assembly genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic