Standard name Systematic name Name description Description
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup57p)
Visualize the interactome of NUP49
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nuc Periphery 0.884 0.787 0.809
Nucleolus 0.211 0.103 0.200
Vac/Vac Memb 0.126 0.135 0.068
Mito NaN 0.097 0.191
Nucleus NaN 0.077 NaN

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 4760

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NUP49 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 16 6 12 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, PCA, Two-hybrid, Far Western, Far Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 15 7 12 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-MS, Far Western, Affinity Capture-MS, Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 11 4 9 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 5 2 5 FRET, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KAP95 YLR347C Karyopherin beta physical 4 4 4 Affinity Capture-Western, Affinity Capture-MS, PCA, Reconstituted Complex
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 3 3 3 Co-purification, Co-fractionation, Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 3 2 3 Two-hybrid, Affinity Capture-MS, Two-hybrid
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 3 2 3 FRET, Affinity Capture-MS, Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 3 2 2 Dosage Rescue, Synthetic Rescue, Synthetic Rescue
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 2 2 2 PCA, Affinity Capture-MS
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 2 2 2 Negative Genetic, Synthetic Lethality
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 2 2 2 Affinity Capture-MS, PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
RMT2 YDR465C Arginine N5 methyltransferase physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 1 1 1 Two-hybrid
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Reconstituted Complex
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Synthetic Rescue
LSM7 YNL147W Lsm (Like Sm) protein physical 1 1 1 Co-localization
MTR10 YOR160W Nuclear import receptor physical 1 1 1 Two-hybrid
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
CDC37 YDR168W Essential Hsp90p co-chaperone physical 1 1 1 Two-hybrid
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 1 1 1 Two-hybrid
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Two-hybrid
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Phenotypic Enhancement
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein physical 1 1 1 Co-localization
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding physical 1 1 1 Two-hybrid
GFD1 YMR255W Coiled-coiled protein of unknown function genetic 1 1 1 Positive Genetic
MSN5 YDR335W Karyopherin physical 1 1 1 Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
IKS1 YJL057C Protein kinase of unknown cellular role physical 1 1 1 Reconstituted Complex
COG6 YNL041C Component of the conserved oligomeric Golgi complex physical 1 1 1 Two-hybrid
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Synthetic Rescue
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p physical 1 1 1 Affinity Capture-MS
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS