Standard name Systematic name Name description Description
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability
Visualize the interactome of OMA1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.548 0.494 0.888
Mito 0.564 0.432 NaN
ER NaN 0.099 NaN
Budneck NaN NaN 0.067

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
OMA1 2 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 2 Negative Genetic, Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 2 Negative Genetic, Negative Genetic
COA2 YPL189C-A Cytochrome oxidase assembly factor genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Co-fractionation
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Negative Genetic
CUP2 YGL166W Copper-binding transcription factor genetic 1 1 1 Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Phenotypic Suppression
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits genetic 1 1 1 Dosage Rescue
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-Western
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Synthetic Growth Defect
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly genetic 1 1 1 Synthetic Rescue
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Synthetic Growth Defect
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Synthetic Growth Defect
PIM1 YBL022C ATP-dependent Lon protease genetic 1 1 1 Dosage Rescue
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Phenotypic Suppression
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Phenotypic Suppression