Standard name Systematic name Name description Description
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication
Visualize the interactome of DBF20
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2/M 133

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.053 NaN 0.096
Cytoplasm 0.908 0.905 0.862
Cell Periphery NaN 0.050 NaN
ER NaN NaN 0.053

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 3320

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DBF20 1 1 2 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 11 4 11 Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic
MOB1 YIL106W Component of the mitotic exit network physical 5 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Proximity Label-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 2 2 2 Positive Genetic, Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
CRN1 YLR429W Coronin genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone physical 1 1 1 Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Phenotypic Enhancement
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 1 1 1 Biochemical Activity
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 PCA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Rescue
NET1 YJL076W Core subunit of the RENT complex genetic 1 1 1 Synthetic Rescue
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation genetic 1 1 1 Synthetic Lethality
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 1 1 1 Positive Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Positive Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Dosage Growth Defect
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
TRP1 YDR007W Phosphoribosylanthranilate isomerase genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Positive Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Phenotypic Suppression
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
BUD16 YEL029C Putative pyridoxal kinase physical 1 1 1 Reconstituted Complex