Standard name Systematic name Name description Description
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1; involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase
Visualize the interactome of SRT1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SRT1 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0286 (cis-prenyltransferase step 06), r_0293 (cis-prenyltransferase step 13), r_0289 (cis-prenyltransferase step 09), r_0283 (cis-prenyltransferase step 03), r_0297 (cis-prenyltransferase step 17), r_0294 (cis-prenyltransferase step 14), r_0290 (cis-prenyltransferase step 10), r_0296 (cis-prenyltransferase step 16), r_0287 (cis-prenyltransferase step 07), r_0295 (cis-prenyltransferase step 15), r_0281 (cis-prenyltransferase step 01), r_0284 (cis-prenyltransferase step 04), r_0298 (cis-prenyltransferase step 18), r_0291 (cis-prenyltransferase step 11), r_0288 (cis-prenyltransferase step 08), r_0282 (cis-prenyltransferase step 02), r_0299 (cis-prenyltransferase step 19), r_0292 (cis-prenyltransferase step 12), r_0285 (cis-prenyltransferase step 05)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 3 2 2 Dosage Rescue, Dosage Rescue, Synthetic Lethality
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SEC59 YMR013C Dolichol kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
CRN1 YLR429W Coronin genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Dosage Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Rescue
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Negative Genetic
SER33 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase genetic 1 1 1 Negative Genetic
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Negative Genetic
CPT1 YNL130C Cholinephosphotransferase genetic 1 1 1 Positive Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Negative Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
OXP1 YKL215C 5-oxoprolinase genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
DCR2 YLR361C Protein phosphatase genetic 1 1 1 Negative Genetic
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
PUN1 YLR414C Plasma membrane protein with a role in cell wall integrity genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Positive Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
SDH8 YBR269C Protein required for assembly of succinate dehydrogenase genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Positive Genetic
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Positive Genetic
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
YER121W YER121W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Negative Genetic
YIL163C YIL163C Protein of unknown function genetic 1 1 1 Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TPO5 YKL174C Protein involved in excretion of putrescine and spermidine genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Negative Genetic
YML037C YML037C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPL034W YPL034W Putative protein of unknown function genetic 1 1 1 Negative Genetic