Standard name Systematic name Name description Description
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate
Visualize the interactome of DSD1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DSD1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4248 (D-serine ammonia-lyase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 2 Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
ARN1 YHL040C ARN family transporter for siderophore-iron chelates genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 2 1 2 Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
SPS2 YDR522C Protein expressed during sporulation genetic 2 1 2 Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Negative Genetic, Negative Genetic
FET5 YFL041W Multicopper oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
ECM29 YHL030W Scaffold protein genetic 2 1 2 Negative Genetic, Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
FRE1 YLR214W Ferric reductase and cupric reductase genetic 2 1 2 Negative Genetic, Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor regulation 2 2 1 chromatin immunoprecipitation- exonuclease evidence, RNA-sequencing evidence
NPL3 YDR432W RNA-binding protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Positive Genetic
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 1 1 1 Negative Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 1 1 1 Synthetic Lethality
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Growth Defect
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 1 1 1 Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Positive Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
GFD2 YCL036W Protein of unknown function genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Negative Genetic
SNA3 YJL151C Protein involved in efficient MVB sorting of proteins to the vacuole genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
SMN1 YHR202W Putative AMP hydrolase genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Negative Genetic
HFL1 YKR051W Vacuole membrane protein that interacts with Atg8p genetic 1 1 1 Negative Genetic
YLR225C YLR225C Putative protein of unknown function genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
YOL029C YOL029C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
YOR292C YOR292C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic