BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
14 |
3 |
10 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
physical |
11 |
5 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-purification |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
10 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-purification |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
9 |
4 |
7 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
9 |
3 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
9 |
3 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
9 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
9 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
9 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
9 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
8 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
8 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
8 |
2 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
7 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
7 |
3 |
6 |
Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
7 |
2 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
7 |
2 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
7 |
3 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
7 |
2 |
4 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
6 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
6 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
6 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
5 |
3 |
5 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
5 |
3 |
4 |
Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
5 |
2 |
4 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic, Positive Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
5 |
2 |
3 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
5 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
physical |
4 |
3 |
3 |
PCA, PCA, Affinity Capture-MS, Co-localization |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
4 |
2 |
3 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
4 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
4 |
2 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
IMH1 |
YLR309C |
Protein involved in vesicular transport |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
EMP24 |
YGL200C |
Component of the p24 complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-localization |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Positive Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
BOP2 |
YLR267W |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Positive Genetic, Phenotypic Enhancement, Phenotypic Enhancement |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Positive Genetic, Phenotypic Enhancement, Phenotypic Enhancement |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRS6 |
YOR370C |
Rab escort protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
RBD2 |
YPL246C |
Possible rhomboid protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
PFY1 |
YOR122C |
Profilin |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
BLM10 |
YFL007W |
Proteasome activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GRH1 |
YDR517W |
Acetylated cis-Golgi protein, homolog of human GRASP65 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FLO8 |
YER109C |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RBK1 |
YCR036W |
Ribokinase, phosphorylates ribose to ribose-5-phosphate |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCP1 |
YOR367W |
Component of yeast cortical actin cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DSL1 |
YNL258C |
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YOL107W |
YOL107W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YND1 |
YER005W |
Apyrase with wide substrate specificity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YPQ1 |
YOL092W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUS1 |
YPL212C |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MAK10 |
YEL053C |
Non-catalytic subunit of the NatC N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRP1 |
YDR347W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL9 |
YGR220C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS120 |
YDR407C |
Component of transport protein particle (TRAPP) complex II |
physical |
1 |
1 |
1 |
Co-purification |
TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
physical |
1 |
1 |
1 |
Co-purification |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Reconstituted Complex |
BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
physical |
1 |
1 |
1 |
PCA |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOD2 |
YHR008C |
Mitochondrial manganese superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAN1 |
YDR143C |
Ubiquitin-protein ligase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
physical |
1 |
1 |
1 |
Two-hybrid |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR078C |
YPR078C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBL036C |
YBL036C |
Putative non-specific single-domain racemase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR284W |
YBR284W |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC3 |
YJL059W |
Protein required for the ATP-dependent transport of arginine |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR028W |
YAR028W |
Putative integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR219C |
YBR219C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL193W |
YJL193W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR034C-A |
YOR034C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRC1 |
YMR243C |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAR4 |
YCL055W |
Transcription factor required for response to pheromones |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET191 |
YJR034W |
Protein required for assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNC1 |
YAL030W |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPB2 |
YAL056W |
Multistep regulator of cAMP-PKA signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Negative Genetic |
HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GEP7 |
YGL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDP1 |
YBR223C |
Tyrosyl-DNA phosphodiesterase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRL1 |
YPR079W |
Membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX22 |
YAL055W |
Putative peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI14 |
YJR013W |
Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
physical |
1 |
1 |
1 |
Co-purification |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG40 |
YOR152C |
Autophagy receptor with a role in endoplasmic reticulum degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL31 |
YBR298C |
Maltose permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM25 |
YDL119C |
Mitochondrial glycine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIG2 |
YIL045W |
Putative type-1 protein phosphatase targeting subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAM41 |
YGR046W |
Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDA2 |
YLR308W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIR2 |
YOR010C |
Putative cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |