Standard name Systematic name Name description Description
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; phosphorylates Cbk1p kinase after allosteric activation by Hym1p; part of the RAM network that regulates cellular polarity and morphogenesis
Visualize the interactome of KIC1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.931 0.96 0.984
ER 0.053 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1040

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KIC1 0 0 2 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HYM1 YKL189W Component of the RAM signaling network physical 8 4 6 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Affinity Capture-Western
SOG2 YOR353C Key component of the RAM signaling network physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 3 3 3 PCA, Affinity Capture-MS, Proximity Label-MS
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 3 2 3 Two-hybrid, Two-hybrid, Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 2 2 2 Synthetic Lethality, Phenotypic Enhancement
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 2 Synthetic Lethality, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 2 2 1 Affinity Capture-Western, Two-hybrid
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge genetic 2 2 1 Phenotypic Enhancement, Synthetic Growth Defect
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Phenotypic Enhancement
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CNA1 YLR433C Calcineurin A physical 1 1 1 Reconstituted Complex
CMP2 YML057W Calcineurin A physical 1 1 1 Reconstituted Complex
HYM1 YKL189W Component of the RAM signaling network genetic 1 1 1 Phenotypic Enhancement
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Two-hybrid
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PIK1 YNL267W Phosphatidylinositol 4-kinase physical 1 1 1 Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex physical 1 1 1 Affinity Capture-MS
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Dosage Rescue
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein genetic 1 1 1 Dosage Rescue
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Growth Defect
SSD1 YDR293C Translational repressor genetic 1 1 1 Synthetic Rescue
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Synthetic Growth Defect
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 1 1 1 Synthetic Growth Defect
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Synthetic Growth Defect
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase physical 1 1 1 Affinity Capture-MS