VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
10 |
3 |
8 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
4 |
1 |
4 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
ADY3 |
YDL239C |
Protein required for spore wall formation |
physical |
3 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, PCA |
VPS5 |
YOR069W |
Nexin-1 homolog |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, PCA |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, PCA |
CDD1 |
YLR245C |
Cytidine deaminase |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YPK1 |
YKL126W |
S/T protein kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPK1 |
YKL126W |
S/T protein kinase |
regulation |
2 |
2 |
1 |
protein kinase assay evidence, qualitative western immunoblotting evidence |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
YML002W |
YML002W |
Putative protein of unknown function |
genetic |
2 |
2 |
1 |
Dosage Rescue, Dosage Growth Defect |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIB1 |
YPR082C |
17-kDa component of the U4/U6aU5 tri-snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISN1 |
YOR155C |
Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase |
physical |
1 |
1 |
1 |
Two-hybrid |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ECM31 |
YBR176W |
Ketopantoate hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCO14 |
YHL018W |
Putative 4a-hydroxytetrahydrobiopterin dehydratase |
physical |
1 |
1 |
1 |
Two-hybrid |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Two-hybrid |
EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
physical |
1 |
1 |
1 |
PCA |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Two-hybrid |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DYS1 |
YHR068W |
Deoxyhypusine synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
CAT2 |
YML042W |
Carnitine acetyl-CoA transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
physical |
1 |
1 |
1 |
Two-hybrid |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Two-hybrid |
NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
physical |
1 |
1 |
1 |
Two-hybrid |
PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
physical |
1 |
1 |
1 |
Two-hybrid |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
1 |
1 |
1 |
Two-hybrid |
SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YJL218W |
YJL218W |
Mitochondrial protein, putative acetyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL088W |
YPL088W |
Putative aryl alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Two-hybrid |
SNO1 |
YMR095C |
Protein of unconfirmed function |
physical |
1 |
1 |
1 |
Two-hybrid |
SNZ3 |
YFL059W |
Pyridoxal-5'-phosphate synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
YIP1 |
YGR172C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT6 |
YLR262C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP1 |
YLR457C |
Spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML003W |
YML003W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRC19 |
YLL033W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTA1 |
YDR256C |
Catalase A |
physical |
1 |
1 |
1 |
Two-hybrid |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |