Standard name Systematic name Name description Description
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS
Visualize the interactome of MCO14
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MCO14 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4189 (4a-hydroxytetrahydrobiopterin hydro-lyase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
RPC19 YNL113W RNA polymerase subunit AC19 physical 2 1 2 Two-hybrid, Two-hybrid
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase physical 2 1 2 Two-hybrid, Two-hybrid
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex physical 1 1 1 Two-hybrid
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
PAU12 YGR294W Protein of unknown function physical 1 1 1 Two-hybrid
PRR2 YDL214C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Two-hybrid
TAE1 YBR261C AdoMet-dependent proline methyltransferase physical 1 1 1 Two-hybrid
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 1 1 1 Two-hybrid
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) physical 1 1 1 Two-hybrid
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex physical 1 1 1 Affinity Capture-RNA
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I genetic 1 1 1 Negative Genetic
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
YCR023C YCR023C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
MFG1 YDL233W Regulator of filamentous growth genetic 1 1 1 Negative Genetic
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Negative Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth genetic 1 1 1 Negative Genetic
YGL176C YGL176C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
YGL242C YGL242C Protein of unknown function genetic 1 1 1 Negative Genetic
STF2 YGR008C Protein involved in resistance to desiccation stress genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
SYM1 YLR251W Protein required for ethanol metabolism genetic 1 1 1 Negative Genetic
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis genetic 1 1 1 Negative Genetic
MRPS17 YMR188C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex genetic 1 1 1 Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Positive Genetic
HNT1 YDL125C Adenosine 5'-monophosphoramidase physical 1 1 1 Two-hybrid
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
EUC1 YMR111C Sequence-specific DNA binding protein physical 1 1 1 Two-hybrid
EUC1 YMR111C Sequence-specific DNA binding protein genetic 1 1 1 Negative Genetic
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
BIO4 YNR057C Dethiobiotin synthetase genetic 1 1 1 Negative Genetic
EMP65 YER140W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis genetic 1 1 1 Negative Genetic