Standard name Systematic name Name description Description
AIP1 YMR092C Actin cortical patch component Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; mutations in human homolog WDR1 are associated with cardiac hypertrophy
Visualize the interactome of AIP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.130 0.101 0.095
Cort. Patches 0.553 0.432 0.538
Cytoplasm 0.193 0.188 0.138
ER 0.122 0.188 0.100
Golgi 0.431 0.478 0.600
Mito 0.055 NaN NaN
Cell Periphery NaN 0.052 NaN
Vac/Vac Memb NaN NaN 0.057

GFP localization & abundance

GFP localization GFP abundance
actin 11100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
AIP1 0 0 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 8 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 7 3 5 Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 6 4 5 Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 6 3 5 Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 6 2 5 Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 6 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 4 3 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Lethality
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 4 2 3 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 2 1 2 Positive Genetic, Positive Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 2 1 2 Negative Genetic, Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 2 1 2 Negative Genetic, Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
CRN1 YLR429W Coronin genetic 2 2 1 Synthetic Lethality, Phenotypic Enhancement
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 2 1 1 Negative Genetic, Negative Genetic
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Two-hybrid
SRV2 YNL138W CAP (cyclase-associated protein) physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Protein-peptide
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase physical 1 1 1 Protein-peptide
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
BUD6 YLR319C Actin- and formin-interacting protein physical 1 1 1 PCA
MSB2 YGR014W Mucin family member involved in various signaling pathways physical 1 1 1 Reconstituted Complex
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Synthetic Growth Defect
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Synthetic Growth Defect
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Positive Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 1 1 1 Negative Genetic
YER134C YER134C Magnesium-dependent acid phosphatase genetic 1 1 1 Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
UFO1 YML088W F-box receptor protein genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Phenotypic Suppression
TWF1 YGR080W Twinfilin genetic 1 1 1 Phenotypic Enhancement
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
AIM7 YDR063W Protein that interacts with Arp2/3 complex genetic 1 1 1 Phenotypic Enhancement