Standard name Systematic name Name description Description
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress
Visualize the interactome of CAP1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.093 0.189 0.167
Cort. Patches 0.539 0.408 0.572
ER 0.066 0.061 NaN
Golgi 0.353 0.138 0.418
Mito 0.632 0.699 0.334
Peroxisome 0.102 0.087 0.273
SpindlePole 0.060 NaN NaN
Cell Periphery NaN NaN 0.058

GFP localization & abundance

GFP localization GFP abundance
actin 4380

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CAP1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 7 4 5 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 6 3 5 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 6 2 5 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
AIP1 YMR092C Actin cortical patch component genetic 6 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 6 2 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 5 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 5 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 3 3 3 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
NUM1 YDR150W Protein required for nuclear migration genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 2 2 2 Synthetic Lethality, Negative Genetic
BNI1 YNL271C Formin genetic 2 2 2 Synthetic Lethality, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
TDA2 YER071C Subunit of a complex that associates with actin filaments physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 2 1 2 Negative Genetic, Negative Genetic
PIL1 YGR086C Eisosome core component genetic 2 1 2 Negative Genetic, Negative Genetic
LAM1 YHR155W Putative sterol transfer protein genetic 2 1 2 Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 2 1 2 Negative Genetic, Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 2 1 1 Two-hybrid, Two-hybrid
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
CMD1 YBR109C Calmodulin genetic 2 1 1 Negative Genetic, Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 2 1 1 Negative Genetic, Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 2 1 1 Negative Genetic, Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 2 1 1 Negative Genetic, Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 2 1 1 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHA4 YLR098C DNA binding transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Phenotypic Enhancement
TWF1 YGR080W Twinfilin physical 1 1 1 Reconstituted Complex
UBP6 YFR010W Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
TFA1 YKL028W TFIIE large subunit physical 1 1 1 Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase physical 1 1 1 Affinity Capture-MS
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis physical 1 1 1 Affinity Capture-MS
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Synthetic Lethality
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Synthetic Growth Defect
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Synthetic Growth Defect
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Dosage Rescue
FLR1 YBR008C Plasma membrane transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Growth Defect
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Synthetic Lethality
CHS1 YNL192W Chitin synthase I genetic 1 1 1 Positive Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SPO14 YKR031C Phospholipase D genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Positive Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Synthetic Growth Defect
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
MRP10 YDL045W-A Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
RPL1B YGL135W Ribosomal 60S subunit protein L1B genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Positive Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Synthetic Rescue
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Synthetic Growth Defect
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 1 1 1 Two-hybrid
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
AIP5 YFR016C Protein that positively regulates actin assembly physical 1 1 1 Affinity Capture-MS
AIP5 YFR016C Protein that positively regulates actin assembly genetic 1 1 1 Negative Genetic
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 1 1 1 Negative Genetic