Standard name Systematic name Name description Description
MSB2 YGR014W Mucin family member involved in various signaling pathways Mucin family member involved in various signaling pathways; functions as osmosensor in the Sho1p-mediated HOG pathway; functions in Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; processed into secreted and cell-associated forms by aspartyl protease Yps1p; potential Cdc28p substrate
Visualize the interactome of MSB2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 56

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.231 0.214 0.316
Vac/Vac Memb 0.708 0.718 0.595
Mito NaN 0.115 0.114
Cytoplasm NaN NaN 0.054

GFP localization & abundance

GFP localization GFP abundance
vacuole 1320

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MSB2 0 0 0 3 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 6 3 5 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 6 2 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
GLN1 YPR035W Glutamine synthetase (GS) physical 4 2 1 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 4 2 1 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 3 3 Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 3 3 3 Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 3 2 3 Negative Genetic, Phenotypic Suppression, Negative Genetic
CDC42 YLR229C Small rho-like GTPase physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 2 1 2 Dosage Rescue, Dosage Rescue
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
SVL3 YPL032C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
MNT2 YGL257C Mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 2 1 Synthetic Lethality, Synthetic Rescue
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 2 1 1 Negative Genetic, Negative Genetic
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Negative Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Reconstituted Complex
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Affinity Capture-Western
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Two-hybrid
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Reconstituted Complex
MAL12 YGR292W Maltase (alpha-D-glucosidase) physical 1 1 1 Reconstituted Complex
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Reconstituted Complex
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
AIP1 YMR092C Actin cortical patch component physical 1 1 1 Reconstituted Complex
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis physical 1 1 1 Reconstituted Complex
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Reconstituted Complex
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels physical 1 1 1 Reconstituted Complex
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery physical 1 1 1 Reconstituted Complex
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Two-hybrid
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase physical 1 1 1 Two-hybrid
IRE1 YHR079C Serine-threonine kinase and endoribonuclease physical 1 1 1 Reconstituted Complex
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Phenotypic Suppression
MAD2 YJL030W Component of the spindle-assembly checkpoint complex physical 1 1 1 Two-hybrid
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex physical 1 1 1 Two-hybrid
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 1 1 1 Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
RCF3 YBR255C-A Mitochondrial inner membrane protein physical 1 1 1 PCA
TYC1 YBR296C-A Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 PCA
UIP3 YAR027W Putative integral membrane protein of unknown function physical 1 1 1 PCA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-RNA
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p genetic 1 1 1 Synthetic Rescue
STE11 YLR362W Signal transducing MEK kinase physical 1 1 1 PCA
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Synthetic Rescue
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Two-hybrid
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 1 1 1 Reconstituted Complex
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex physical 1 1 1 Reconstituted Complex
SKI8 YGL213C Ski complex component and WD-repeat protein physical 1 1 1 Reconstituted Complex
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Reconstituted Complex
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 1 1 1 Phenotypic Suppression
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Phenotypic Enhancement
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 1 1 1 Synthetic Lethality
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Synthetic Lethality
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Synthetic Rescue
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
RSR1 YGR152C Ras-type GTPase genetic 1 1 1 Phenotypic Enhancement
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Rescue
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Phenotypic Suppression
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Rescue
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p physical 1 1 1 Reconstituted Complex
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Two-hybrid
CAN1 YEL063C Plasma membrane arginine permease physical 1 1 1 PCA
MIG2 YGL209W Zinc finger transcriptional repressor physical 1 1 1 Two-hybrid
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
FRD1 YEL047C Soluble fumarate reductase physical 1 1 1 Reconstituted Complex
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
MAL32 YBR299W Maltase (alpha-D-glucosidase) physical 1 1 1 Reconstituted Complex