CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
4 |
1 |
4 |
Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
MCM1 |
YMR043W |
Transcription factor |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
3 |
1 |
Positive Genetic, Synthetic Rescue, Dosage Growth Defect |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
3 |
3 |
1 |
Positive Genetic, Synthetic Rescue, Dosage Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Rescue |
CDC53 |
YDL132W |
Cullin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MBP1 |
YDL056W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CIP1 |
YPL014W |
Cyclin-dependent kinase inhibitor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BSC3 |
YLR465C |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HST4 |
YDR191W |
NAD(+)-dependent protein deacetylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MCM3 |
YEL032W |
Protein involved in DNA replication |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YLR297W |
YLR297W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YLR162W |
YLR162W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YFL064C |
YFL064C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PIG1 |
YLR273C |
Putative targeting subunit for type-1 protein phosphatase Glc7p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB4 |
YMR019W |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGO1 |
YDR470C |
Outer membrane component of the mitochondrial fusion machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPC2 |
YDR213W |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL194C |
YNL194C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR225C |
YLR225C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |