Standard name Systematic name Name description Description
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor Mitochondrial cytochrome c oxidase (complex IV) assembly factor; also involved in translational regulation of Cox1p and prevention of Cox1p aggregation before assembly; associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; located in the mitochondrial membrane
Visualize the interactome of COX14
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.082 NaN NaN
Golgi 0.257 0.353 NaN
Mito 0.574 0.571 NaN
Vac/Vac Memb 0.342 0.156 NaN
Cell Periphery NaN 0.089 NaN
Cort. Patches NaN 0.071 NaN
ER NaN 0.121 NaN

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 6840

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COX14 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA physical 9 1 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly physical 6 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 6 1 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
COA1 YIL157C Mitochondrial inner membrane protein physical 5 1 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
COX1 Q0045 Subunit I of cytochrome c oxidase (Complex IV) physical 4 1 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 4 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
COX3 Q0275 Subunit III of cytochrome c oxidase (Complex IV) physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RIP1 YEL024W Ubiquinol-cytochrome-c reductase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
PMP3 YDR276C Small plasma membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MDR1 YGR100W Cytoplasmic GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
RGT1 YKL038W Glucose-responsive transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 2 1 2 Negative Genetic, Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 2 1 2 Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
COA2 YPL189C-A Cytochrome oxidase assembly factor genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Phenotypic Suppression
COB Q0105 Cytochrome b physical 1 1 1 Affinity Capture-Western
ATP6 Q0085 Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-Western
COS3 YML132W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
CYT1 YOR065W Cytochrome c1 physical 1 1 1 Affinity Capture-Western
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex physical 1 1 1 Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YAR028W YAR028W Putative integral membrane protein physical 1 1 1 PCA
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 Affinity Capture-Western
COX5A YNL052W Subunit Va of cytochrome c oxidase physical 1 1 1 Affinity Capture-Western
COX5B YIL111W Subunit Vb of cytochrome c oxidase physical 1 1 1 Affinity Capture-Western
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
CYC1 YJR048W Cytochrome c, isoform 1 genetic 1 1 1 Phenotypic Suppression
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions genetic 1 1 1 Phenotypic Suppression
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
FLO1 YAR050W Lectin-like protein involved in flocculation genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
YMR316C-A YMR316C-A Protein of unknown function genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
YOL013W-A YOL013W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Phenotypic Suppression
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
COX11 YPL132W Protein required for delivery of copper to Cox1p genetic 1 1 1 Phenotypic Enhancement
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS