Standard name Systematic name Name description Description
COS3 YML132W Endosomal protein involved in turnover of plasma membrane proteins Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
Visualize the interactome of COS3
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1 222

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.764 0.819 0.773
Nucleus 0.069 NaN NaN
Vac/Vac Memb 0.203 0.125 0.193
Mito NaN 0.083 0.084

GFP localization & abundance

GFP localization GFP abundance
vacuole 639

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COS3 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
NHA1 YLR138W Na+/H+ antiporter physical 2 2 1 Affinity Capture-Western, Co-fractionation
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 DNA to cDNA expression microarray evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
YRO2 YBR054W Protein with a putative role in response to acid stress physical 1 1 1 PCA
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 PCA
SHR3 YDL212W Endoplasmic reticulum packaging chaperone physical 1 1 1 PCA
VMA16 YHR026W Subunit c'' of the vacuolar ATPase physical 1 1 1 PCA
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine physical 1 1 1 PCA
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor physical 1 1 1 PCA
THI72 YOR192C Transporter of thiamine or related compound physical 1 1 1 PCA
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Positive Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Synthetic Rescue