Standard name Systematic name Name description Description
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage Trifunctional enzyme of thiamine biosynthesis, degradation and salvage; has hydroxymethylpyrimidine (HMP) kinase, HMP-phosphate (HMP-P) kinase and thiaminase activities; member of a gene family with THI21 and THI22; HMP and HMP-P kinase activity redundant with Thi21p
Visualize the interactome of THI20
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.975 0.976 0.963
Mito 0.076 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
ambiguous 195

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
THI20 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0561 (hydroxymethylpyrimidine kinase (ATP)), r_0903 (phosphomethylpyrimidine kinase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
YEA6 YEL006W Mitochondrial NAD+ transporter genetic 2 1 2 Positive Genetic, Positive Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDC2 YDR081C Transcription factor for thiamine-regulated genes regulation 1 1 1 northern blot evidence
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Positive Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex physical 1 1 1 Affinity Capture-MS
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination physical 1 1 1 Affinity Capture-MS
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Negative Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Affinity Capture-MS
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Negative Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease physical 1 1 1 Affinity Capture-MS
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SDH3 YKL141W Subunit of succinate dehydrogenase and of TIM22 translocase genetic 1 1 1 Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Positive Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
MEP3 YPR138C Ammonium permease of high capacity and low affinity genetic 1 1 1 Positive Genetic
PBI1 YPL272C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MPH3 YJR160C Alpha-glucoside permease genetic 1 1 1 Positive Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Positive Genetic
PRM7 YDL039C Pheromone-regulated protein genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
THI21 YPL258C Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase genetic 1 1 1 Phenotypic Enhancement
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase genetic 1 1 1 Positive Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Positive Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Positive Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Positive Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
URH1 YDR400W Uridine nucleosidase (uridine-cytidine N-ribohydrolase) genetic 1 1 1 Negative Genetic
ZRT3 YKL175W Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
YLR012C YLR012C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p genetic 1 1 1 Negative Genetic
YHB1 YGR234W Nitric oxide oxidoreductase genetic 1 1 1 Negative Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic