Standard name Systematic name Name description Description
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
Visualize the interactome of RFC5
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 56

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.902 0.908 0.926
Mito NaN 0.065 0.075
Nuc Periphery NaN 0.065 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleus 5040

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RFC5 0 1 0 0 1

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ELG1 YOR144C Subunit of an alternative replication factor C complex physical 9 3 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) physical 8 5 7 Reconstituted Complex, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Two-hybrid
RAD24 YER173W Checkpoint protein physical 8 5 6 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification, Co-fractionation, Co-purification
CTF18 YMR078C Subunit of a complex with Ctf8p physical 7 4 6 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-purification
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 7 2 5 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 6 2 5 Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 5 3 5 Reconstituted Complex, Reconstituted Complex, FRET, Co-crystal Structure, Reconstituted Complex
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 5 2 5 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 5 4 4 Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 4 2 4 Dosage Rescue, Negative Genetic, Dosage Rescue, Negative Genetic
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RTT109 YLL002W Histone acetyltransferase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 3 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 2 2 Positive Genetic, Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 2 2 Synthetic Rescue, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 2 2 Synthetic Lethality, Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 2 2 2 Positive Genetic, Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 2 2 2 Negative Genetic, Positive Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 2 2 Synthetic Lethality, Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 2 2 Synthetic Lethality, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 1 2 Positive Genetic, Positive Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 2 1 2 Negative Genetic, Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 1 2 Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
HHT1 YBR010W Histone H3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 2 Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 2 1 2 Negative Genetic, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 2 1 2 Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 2 1 2 Negative Genetic, Negative Genetic
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
PRI1 YIR008C Subunit of DNA primase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 2 1 2 Negative Genetic, Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 2 1 1 Negative Genetic, Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 2 1 1 Negative Genetic, Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 2 1 1 Negative Genetic, Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DAL82 YNL314W Positive regulator of allophanate inducible genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Positive Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Synthetic Growth Defect
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor physical 1 1 1 Affinity Capture-Western
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Phenotypic Enhancement
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Synthetic Lethality
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Synthetic Growth Defect
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Synthetic Growth Defect
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Synthetic Lethality
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Dosage Lethality
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Synthetic Lethality
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
YMR181C YMR181C Protein of unknown function physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
SEC65 YML105C Subunit of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Dosage Rescue
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Negative Genetic
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Negative Genetic
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Synthetic Lethality
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
UGO1 YDR470C Outer membrane component of the mitochondrial fusion machinery genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
ZUO1 YGR285C Ribosome-associated chaperone genetic 1 1 1 Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
YML100W-A YML100W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Positive Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
RNH203 YLR154C Ribonuclease H2 subunit genetic 1 1 1 Negative Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Synthetic Growth Defect
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
LSM12 YHR121W Protein of unknown function that may function in RNA processing genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping genetic 1 1 1 Negative Genetic
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Phenotypic Suppression
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic genetic 1 1 1 Synthetic Lethality
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria physical 1 1 1 Affinity Capture-Western
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Phenotypic Enhancement
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
RAD24 YER173W Checkpoint protein genetic 1 1 1 Dosage Rescue
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Synthetic Lethality
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Negative Genetic
MSS116 YDR194C Mitochondrial transcription elongation factor genetic 1 1 1 Positive Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Synthetic Lethality
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Suppression
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p physical 1 1 1 Affinity Capture-Western
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion physical 1 1 1 Affinity Capture-Western
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Positive Genetic
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Negative Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Two-hybrid
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 1 1 1 Positive Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly physical 1 1 1 Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Positive Genetic
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Positive Genetic
COA1 YIL157C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Synthetic Growth Defect
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Positive Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Positive Genetic
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Phenotypic Enhancement
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic