Standard name Systematic name Name description Description
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant
Visualize the interactome of CCS1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.992 0.995 0.991

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CCS1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 8 5 7 Reconstituted Complex, Two-hybrid, Two-hybrid, Co-crystal Structure, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 6 2 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 4 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 4 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 4 3 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 3 3 3 Positive Genetic, Phenotypic Enhancement, Phenotypic Suppression
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
CDC73 YLR418C Component of the Paf1p complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 3 3 2 Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 3 3 2 Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
RAD55 YDR076W Protein that stimulates strand exchange genetic 3 3 2 Negative Genetic, Synthetic Lethality, Synthetic Growth Defect
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
DIA2 YOR080W Origin-binding F-box protein genetic 3 2 2 Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
GET2 YER083C Subunit of the GET complex genetic 3 2 2 Negative Genetic, Synthetic Lethality, Synthetic Lethality
POL32 YJR043C Third subunit of DNA polymerase delta genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
RAD57 YDR004W Protein that stimulates strand exchange genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 3 2 2 Negative Genetic, Synthetic Lethality, Synthetic Lethality
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
CTF4 YPR135W Chromatin-associated protein genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HTA1 YDR225W Histone H2A genetic 2 2 2 Negative Genetic, Synthetic Lethality
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p physical 2 2 1 Co-purification, Co-crystal Structure
GET1 YGL020C Subunit of the GET complex genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Lethality
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 1 1 1 Synthetic Lethality
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Growth Defect
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Synthetic Lethality
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Synthetic Lethality
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
SGO1 YOR073W Component of the spindle checkpoint genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Negative Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
SAN1 YDR143C Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
PZF1 YPR186C Transcription factor IIIA (TFIIIA) genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Positive Genetic
GON7 YJL184W Component of the EKC/KEOPS protein complex genetic 1 1 1 Positive Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Rescue
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Synthetic Growth Defect
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
LYP1 YNL268W Lysine permease genetic 1 1 1 Synthetic Lethality
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Synthetic Lethality
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Synthetic Lethality
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Synthetic Lethality
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Growth Defect
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Synthetic Growth Defect
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 1 1 1 Synthetic Growth Defect
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Synthetic Growth Defect
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Synthetic Growth Defect
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Synthetic Growth Defect
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Growth Defect
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Growth Defect
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Synthetic Growth Defect
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Lethality
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Lethality
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Lethality
HEM14 YER014W Protoporphyrinogen oxidase genetic 1 1 1 Synthetic Lethality
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Lethality
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Lethality
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Lethality
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Synthetic Lethality
YLR278C YLR278C Zinc-cluster protein genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Growth Defect
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
HHT1 YBR010W Histone H3 genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic