Standard name Systematic name Name description Description
TIM17 YJL143W Essential component of the TIM23 complex Essential component of the TIM23 complex; with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core Translocase of the Inner Mitochondrial membrane (TIM23 complex)
Visualize the interactome of TIM17
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.949 0.964 0.968

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1210

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TIM17 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TIM23 YNR017W Essential component of the TIM23 complex physical 47 5 41 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
PAM16 YJL104W Subunit of the import motor (PAM complex) physical 15 3 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
TIM44 YIL022W Essential component of the TIM23 complex physical 9 3 8 Affinity Capture-Western, Co-fractionation, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
TIM50 YPL063W Essential component of the TIM23 complex physical 9 2 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
TIM21 YGR033C Nonessential component of the TIM23 complex physical 9 1 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
PAM18 YLR008C Subunit of the import motor (PAM complex) physical 8 2 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
TIM23 YNR017W Essential component of the TIM23 complex genetic 7 4 6 Dosage Rescue, Synthetic Lethality, Dosage Rescue, Dosage Rescue, Phenotypic Suppression, Dosage Rescue, Negative Genetic
SSC1 YJR045C Hsp70 family ATPase physical 6 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
PAM17 YKR065C Constituent of the TIM23 complex physical 4 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
TIM44 YIL022W Essential component of the TIM23 complex genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 2 2 2 Dosage Rescue, Synthetic Lethality
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 2 2 2 Synthetic Lethality, Synthetic Rescue
PAM17 YKR065C Constituent of the TIM23 complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
SSC1 YJR045C Hsp70 family ATPase genetic 2 2 1 Dosage Rescue, Synthetic Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space physical 1 1 1 Affinity Capture-Western
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 1 1 1 Affinity Capture-Western
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-Western
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-Western
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
TIM17 YJL143W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-Western
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Dosage Rescue
CYB2 YML054C Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) physical 1 1 1 Affinity Capture-Western
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-Western
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
ERV1 YGR029W Flavin-linked sulfhydryl oxidase of the mitochondrial IMS physical 1 1 1 Affinity Capture-Western
MIX23 YBL107C Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS