Standard name Systematic name Name description Description
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bacteria
Visualize the interactome of TDH1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.430 0.208 0.482
Mito 0.115 NaN 0.071
Nucleus 0.255 0.104 0.107
Vac/Vac Memb 0.415 0.784 0.536

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 120000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TDH1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0486 (glyceraldehyde-3-phosphate dehydrogenase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SUP35 YDR172W Translation termination factor eRF3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
MPS3 YJL019W Nuclear envelope protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
INO2 YDR123C Transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Co-purification
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 1 1 1 Affinity Capture-MS
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Affinity Capture-MS
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Co-fractionation
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Affinity Capture-MS
RIE1 YGR250C RNA binding protein and negative regulator of START physical 1 1 1 Affinity Capture-MS
RIE1 YGR250C RNA binding protein and negative regulator of START genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
SAN1 YDR143C Ubiquitin-protein ligase physical 1 1 1 Two-hybrid
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
CCP1 YKR066C Mitochondrial cytochrome-c peroxidase physical 1 1 1 Affinity Capture-MS
ACF2 YLR144C Intracellular beta-1,3-endoglucanase physical 1 1 1 Affinity Capture-MS
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
GTT2 YLL060C Glutathione S-transferase capable of homodimerization physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Proximity Label-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter physical 1 1 1 Co-fractionation
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Proximity Label-MS
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
YEL023C YEL023C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
UTH1 YKR042W Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Positive Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA physical 1 1 1 Affinity Capture-MS
RPM2 YML091C Protein subunit of mitochondrial RNase P physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
AHC2 YCR082W Component of the ADA histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Rescue
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Positive Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Phenotypic Suppression
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
SOL4 YGR248W 6-phosphogluconolactonase genetic 1 1 1 Positive Genetic
MRX15 YNR040W Membrane-associated mitoribosome receptor physical 1 1 1 Proximity Label-MS