Standard name Systematic name Name description Description
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; is essential for translation; stimulates resumption of ribosomal scanning during translation reinitiation; eIF3 is also involved in programmed stop codon readthrough
Visualize the interactome of TIF35
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.129 0.075 0.203
Mito 0.099 0.575 NaN
Nucleus 0.673 0.512 0.660
Vac/Vac Memb 0.178 0.100 0.057
Endosome NaN 0.050 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TIF35 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 20 7 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 19 6 13 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Co-fractionation, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 13 4 11 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 7 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) physical 6 3 4 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SUI1 YNL244C Translation initiation factor eIF1 physical 4 3 4 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
TIF5 YPR041W Translation initiation factor eIF5 physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 3 3 3 Co-fractionation, Affinity Capture-MS, Affinity Capture-Western
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RLI1 YDR091C Essential Fe-S protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 2 1 2 Dosage Rescue, Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 2 1 Two-hybrid, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Positive Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Positive Genetic
ECM2 YBR065C Pre-mRNA splicing factor physical 1 1 1 Affinity Capture-MS
NOP15 YNL110C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-Western
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Negative Genetic
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-Western
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
NRP1 YDL167C Putative RNA binding protein of unknown function genetic 1 1 1 Positive Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Synthetic Growth Defect
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Positive Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Reconstituted Complex
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-Western
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
SUI1 YNL244C Translation initiation factor eIF1 genetic 1 1 1 Dosage Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 Reconstituted Complex
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Positive Genetic
DUF1 YOL087C Ubiquitin-binding protein of unknown function physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase physical 1 1 1 Two-hybrid
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Proximity Label-MS
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
TIF3 YPR163C Translation initiation factor eIF-4B physical 1 1 1 Two-hybrid
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Proximity Label-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
TDA2 YER071C Subunit of a complex that associates with actin filaments physical 1 1 1 Affinity Capture-MS
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution physical 1 1 1 Two-hybrid
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Dosage Growth Defect
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
NNT1 YLR285W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic