Standard name Systematic name Name description Description
ECM2 YBR065C Pre-mRNA splicing factor Pre-mRNA splicing factor; facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p
Visualize the interactome of ECM2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.173 NaN NaN
Nucleus 0.938 0.951 0.949

GFP localization & abundance

GFP localization GFP abundance
nucleus 4260

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ECM2 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CEF1 YMR213W Essential splicing factor physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP19 YLL036C Splicing factor associated with the spliceosome physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
PML1 YLR016C Subunit of the RES complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PYP1 YNL010W Sugar alcohol phosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AEP2 YMR282C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 2 2 Synthetic Lethality, Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 2 2 2 Negative Genetic, Synthetic Lethality
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 2 1 2 Negative Genetic, Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 2 1 2 Negative Genetic, Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RTN1 YDR233C Reticulon protein genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 2 1 2 Negative Genetic, Negative Genetic
PYC1 YGL062W Pyruvate carboxylase isoform genetic 2 1 2 Negative Genetic, Negative Genetic
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase genetic 2 1 2 Negative Genetic, Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 2 Negative Genetic, Negative Genetic
MPC3 YGR243W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 2 1 2 Positive Genetic, Positive Genetic
VHS2 YIL135C Regulator of septin dynamics genetic 2 1 2 Negative Genetic, Negative Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 2 1 2 Negative Genetic, Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 2 1 2 Negative Genetic, Negative Genetic
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering genetic 2 1 2 Negative Genetic, Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 2 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 2 Negative Genetic, Negative Genetic
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 2 1 2 Negative Genetic, Negative Genetic
DOG1 YHR044C 2-deoxyglucose-6-phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 2 Negative Genetic, Negative Genetic
AQY3 YFL054C Putative channel-like protein genetic 2 1 2 Negative Genetic, Negative Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 2 2 1 Synthetic Rescue, Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
SUL1 YBR294W High affinity sulfate permease of the SulP anion transporter family genetic 2 1 1 Negative Genetic, Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 2 1 1 Negative Genetic, Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 2 1 1 Negative Genetic, Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 2 1 1 Negative Genetic, Negative Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 2 1 1 Negative Genetic, Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
FLX1 YIL134W Mitochondrial flavin adenine dinucleotide transporter genetic 2 1 1 Negative Genetic, Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 2 1 1 Negative Genetic, Negative Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 1 1 1 Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F physical 1 1 1 Affinity Capture-MS
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
SLU7 YDR088C RNA splicing factor physical 1 1 1 Affinity Capture-Western
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
LSP1 YPL004C Eisosome core component physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Synthetic Growth Defect
PRP16 YKR086W DEAH-box RNA helicase physical 1 1 1 Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 1 1 1 Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
ECM2 YBR065C Pre-mRNA splicing factor physical 1 1 1 Reconstituted Complex
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 1 1 1 Reconstituted Complex
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 1 1 1 Positive Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Positive Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Positive Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein genetic 1 1 1 Negative Genetic
YBR287W YBR287W Protein of unknown function genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
UBP5 YER144C Putative ubiquitin-specific protease genetic 1 1 1 Positive Genetic
GCG1 YER163C Gamma-glutamyl cyclotransferase genetic 1 1 1 Negative Genetic
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Negative Genetic
FMP32 YFL046W Regulator of mitochondrial proline metabolism genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity genetic 1 1 1 Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
RDL2 YOR286W Protein with rhodanese activity genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
MMO1 YKL044W Protein of unknown function genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
YKR104W YKR104W Putative transporter of the MRP subfamily genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
SYM1 YLR251W Protein required for ethanol metabolism genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
IMD4 YML056C Inosine monophosphate dehydrogenase genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PEX9 YMR018W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Negative Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
RPL31B YLR406C Ribosomal 60S subunit protein L31B genetic 1 1 1 Negative Genetic
YMR244W YMR244W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ATG29 YPL166W Autophagy-specific protein genetic 1 1 1 Negative Genetic
CMP2 YML057W Calcineurin A genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
CHS1 YNL192W Chitin synthase I genetic 1 1 1 Synthetic Growth Defect
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Positive Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Negative Genetic
ATO2 YNR002C Putative transmembrane protein involved in export of ammonia genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Positive Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
ATG22 YCL038C Vacuolar integral membrane protein required for efflux of amino acids genetic 1 1 1 Negative Genetic