Standard name Systematic name Name description Description
RQC1 YDR333C Component of the ribosome quality control complex (RQC) Component of the ribosome quality control complex (RQC); RQC (Rqc1p-Rkr1p-Rqc2p-Cdc48p-Npl4p-Ufd1p) is a ribosome-bound complex required for the degradation of polypeptides arising from stalled translation; required along with Rkr1p for recruitment of the Cdc48p-Npl4p-Ufd1p AAA ATPase complex to the RQC
Visualize the interactome of RQC1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.971 0.98 0.984
Budneck NaN NaN 0.053

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RQC1 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RKR1 YMR247C RING domain E3 ubiquitin ligase physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex genetic 3 1 3 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression
UBI4 YLL039C Ubiquitin physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL32 YBL092W Ribosomal 60S subunit protein L32 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPP2B YDR382W Ribosomal protein P2 beta physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPP2A YOL039W Ribosomal protein P2 alpha physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 2 Negative Genetic, Negative Genetic
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERB1 YMR049C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL38 YLR325C Ribosomal 60S subunit protein L38 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Positive Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Dosage Rescue
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Rescue
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Affinity Capture-MS
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 1 1 1 Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPP1A YDL081C Ribosomal stalk protein P1 alpha physical 1 1 1 Affinity Capture-MS
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Affinity Capture-MS
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 Affinity Capture-MS
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL43A YPR043W Ribosomal 60S subunit protein L43A physical 1 1 1 Affinity Capture-MS
RPL36A YMR194W Ribosomal 60S subunit protein L36A physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
RPP1B YDL130W Ribosomal protein P1 beta physical 1 1 1 Affinity Capture-MS
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase physical 1 1 1 Affinity Capture-MS
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
RQC1 YDR333C Component of the ribosome quality control complex (RQC) physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Lethality
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHK8 YHR048W Presumed antiporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Synthetic Rescue