Standard name Systematic name Name description Description
TRP3 YKL211C Indole-3-glycerol-phosphate synthase Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
Visualize the interactome of TRP3
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.995 0.991 0.994

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 13400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TRP3 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0203 (anthranilate synthase), r_0566 (indole-3-glycerol-phosphate synthase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 6 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRP2 YER090W Anthranilate synthase physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MSH4 YFL003C Protein involved in meiotic recombination genetic 2 1 2 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 2 1 2 Negative Genetic, Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Positive Genetic, Positive Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 2 1 2 Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 1 1 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Reconstituted Complex
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
TKL1 YPR074C Transketolase genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Reconstituted Complex
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair physical 1 1 1 Affinity Capture-MS
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Reconstituted Complex
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Reconstituted Complex
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Reconstituted Complex
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Negative Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Reconstituted Complex
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Two-hybrid
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 PCA
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAM1 YJR069C Nucleoside triphosphate pyrophosphohydrolase genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
EKI1 YDR147W Ethanolamine kinase genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
ALD2 YMR170C Cytoplasmic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Positive Genetic
SKS1 YPL026C Putative serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
MUP3 YHL036W Low affinity methionine permease genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
LPX1 YOR084W Peroxisomal matrix-localized lipase genetic 1 1 1 Negative Genetic
DAL4 YIR028W Allantoin permease genetic 1 1 1 Positive Genetic
QCR10 YHR001W-A Subunit of the ubiqunol-cytochrome c oxidoreductase complex genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic