Standard name Systematic name Name description Description
SBH2 YER019C-A Ssh1p-Sss1p-Sbh2p complex component Ssh1p-Sss1p-Sbh2p complex component; involved in protein translocation into the endoplasmic reticulum; SBH2 has a paralog, SBH1, that arose from the whole genome duplication
Visualize the interactome of SBH2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.084 NaN 0.102
Cytoplasm 0.092 0.055 NaN
ER 0.680 0.805 0.764
Vac/Vac Memb 0.278 0.140 0.096
Golgi NaN 0.059 NaN
Nuc Periphery NaN 0.106 0.083
Mito NaN NaN 0.334

GFP localization & abundance

GFP localization GFP abundance
ER 414

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SBH2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) genetic 9 4 8 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
GET2 YER083C Subunit of the GET complex genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 2 1 2 Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 2 1 2 Negative Genetic, Negative Genetic
BDH1 YAL060W NAD-dependent (R,R)-butanediol dehydrogenase genetic 2 1 2 Positive Genetic, Positive Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen physical 2 2 1 PCA, Affinity Capture-Western
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 1 Negative Genetic, Negative Genetic
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) genetic 2 1 1 Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
SRP72 YPL210C Core component of the signal recognition particle (SRP) genetic 2 1 1 Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 1 1 Negative Genetic, Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 DNA to cDNA expression microarray evidence
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen physical 1 1 1 PCA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex physical 1 1 1 Two-hybrid
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 Affinity Capture-Western
SPC2 YML055W Subunit of signal peptidase complex physical 1 1 1 Affinity Capture-Western
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l physical 1 1 1 PCA
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 PCA
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 PCA
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Enhancement
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Enhancement
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Synthetic Growth Defect
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Synthetic Growth Defect
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex physical 1 1 1 PCA
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen physical 1 1 1 PCA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic