Standard name Systematic name Name description Description
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome Non-ATPase regulatory subunit of the 26S proteasome; similar to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia
Visualize the interactome of RPN9
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.069 0.064 NaN
Nucleus 0.843 0.795 0.783
Vac/Vac Memb 0.083 0.205 0.123

GFP localization & abundance

GFP localization GFP abundance
nucleus 12400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RPN9 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 22 5 21 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 15 5 14 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN10 YHR200W Proteasome polyubiquitin receptor physical 12 6 9 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Reconstituted Complex, Reconstituted Complex, PCA
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 11 4 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 7 3 6 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 6 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 6 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 5 2 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 4 2 4 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPN2 YIL075C Subunit of the 26S proteasome physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UBP6 YFR010W Ubiquitin-specific protease physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ECM29 YHL030W Scaffold protein physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN14 YGL004C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 Two-hybrid
YGR067C YGR067C Putative protein of unknown function physical 1 1 1 Two-hybrid
VAC14 YLR386W Enzyme regulator physical 1 1 1 Two-hybrid
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
SPG5 YMR191W Protein required for proteasome assembly during quiescence physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
TIP41 YPR040W Tap42p-interacting protein physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
INO80 YGL150C Nucleosome spacing factor physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Dosage Lethality
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
KAP122 YGL016W Karyopherin beta physical 1 1 1 Affinity Capture-MS
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
DDI1 YER143W Aspartic-type endopeptidase physical 1 1 1 Affinity Capture-Western
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Synthetic Rescue
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
NPT1 YOR209C Nicotinate phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS