Standard name Systematic name Name description Description
PEP12 YOR036W Target membrane receptor (t-SNARE) Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin
Visualize the interactome of PEP12
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PEP12 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 9 3 8 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 4 3 4 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic physical 4 2 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 4 3 2 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Synthetic Rescue
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi physical 3 3 3 Affinity Capture-Western, Reconstituted Complex, Co-purification
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance genetic 3 3 2 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement
CHC1 YGL206C Clathrin heavy chain genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 2 2 2 Affinity Capture-MS, Two-hybrid
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 2 1 2 Negative Genetic, Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 2 1 2 Dosage Rescue, Dosage Rescue
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 1 2 Negative Genetic, Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 2 1 2 Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 2 1 2 Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 1 2 Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 2 1 2 Negative Genetic, Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 2 1 2 Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MAY24 YPR153W Peripheral ER membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I physical 1 1 1 Affinity Capture-MS
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Synthetic Growth Defect
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p physical 1 1 1 Co-crystal Structure
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Affinity Capture-MS
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Rescue
DAP1 YPL170W Heme-binding protein physical 1 1 1 Co-fractionation
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Dosage Growth Defect
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
YPT1 YFL038C Rab family GTPase physical 1 1 1 Two-hybrid
YPT31 YER031C Rab family GTPase physical 1 1 1 Two-hybrid
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-Western
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Dosage Lethality
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting physical 1 1 1 Affinity Capture-Western
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 1 1 1 Phenotypic Enhancement
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) physical 1 1 1 Affinity Capture-Western
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Lethality
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Synthetic Lethality
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex physical 1 1 1 Affinity Capture-Western
VAM7 YGL212W Vacuolar SNARE protein physical 1 1 1 Reconstituted Complex
SST2 YLR452C GTPase-activating protein for Gpa1p physical 1 1 1 Two-hybrid
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Two-hybrid
SFT1 YKL006C-A Intra-Golgi v-SNARE physical 1 1 1 Reconstituted Complex
SED5 YLR026C cis-Golgi t-SNARE syntaxin physical 1 1 1 Co-fractionation
YPT35 YHR105W Endosomal protein of unknown function physical 1 1 1 Two-hybrid
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi physical 1 1 1 Two-hybrid
YJR015W YJR015W Putative protein of unknown function physical 1 1 1 PCA
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Co-purification
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Synthetic Lethality
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
VPS8 YAL002W Membrane-binding component of the CORVET complex physical 1 1 1 Reconstituted Complex
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) physical 1 1 1 Reconstituted Complex
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Lethality
SEC22 YLR268W R-SNARE protein physical 1 1 1 Reconstituted Complex
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Enhancement
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Synthetic Lethality
PHO8 YDR481C Repressible vacuolar alkaline phosphatase genetic 1 1 1 Phenotypic Enhancement
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Phenotypic Enhancement
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 1 1 1 Phenotypic Enhancement
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Phenotypic Enhancement
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
PIL1 YGR086C Eisosome core component genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
SES1 YDR023W Cytosolic seryl-tRNA synthetase genetic 1 1 1 Negative Genetic
SAL1 YNL083W ADP/ATP transporter genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Phenotypic Enhancement
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Synthetic Growth Defect
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Reconstituted Complex
GOS1 YHL031C v-SNARE protein involved in Golgi transport physical 1 1 1 Reconstituted Complex
GAP1 YKR039W General amino acid permease physical 1 1 1 Co-purification
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation physical 1 1 1 Affinity Capture-MS
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Co-purification
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Phenotypic Enhancement
ENT5 YDR153C Protein containing an N-terminal epsin-like domain physical 1 1 1 Affinity Capture-MS
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Positive Genetic
EMP70 YLR083C Protein with a role in cellular adhesion and filamentous growth physical 1 1 1 PCA
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
COQ3 YOL096C O-methyltransferase genetic 1 1 1 Phenotypic Enhancement
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Phenotypic Enhancement
LOA1 YPR139C Lysophosphatidic acid acyltransferase physical 1 1 1 Co-fractionation
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
BAP2 YBR068C High-affinity leucine permease physical 1 1 1 Co-fractionation
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
CQD2 YLR253W Mitochondrial protein involved in lipid homeostasis genetic 1 1 1 Positive Genetic