Standard name Systematic name Name description Description
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit Mitochondrial ribosomal protein of the large subunit; mutation confers increased replicative lifespan
Visualize the interactome of MRPL25
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.943 0.870 0.972
Vac/Vac Memb 0.143 0.219 0.083
Nuc Periphery NaN NaN 0.055

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 1550

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MRPL25 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Proximity Label-MS
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRP4 YHL004W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
YLH47 YPR125W Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Co-fractionation
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Synthetic Rescue
OPT2 YPR194C Oligopeptide transporter genetic 1 1 1 Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Positive Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Dosage Rescue
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Positive Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Affinity Capture-MS
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS