GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
physical |
9 |
4 |
7 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Biochemical Activity, Two-hybrid, Affinity Capture-MS |
CHC1 |
YGL206C |
Clathrin heavy chain |
genetic |
4 |
3 |
2 |
Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Synthetic Lethality |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
3 |
2 |
2 |
Two-hybrid, Affinity Capture-Western, Two-hybrid |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
physical |
3 |
3 |
1 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
PRK1 |
YIL095W |
Ser/Thr protein kinase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Two-hybrid |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
1 |
1 |
1 |
Two-hybrid |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
physical |
1 |
1 |
1 |
Two-hybrid |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BIK1 |
YCL029C |
Microtubule-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PRK1 |
YIL095W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Two-hybrid |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
physical |
1 |
1 |
1 |
Two-hybrid |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YNL092W |
YNL092W |
S-adenosylmethionine-dependent protein methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
1 |
1 |
1 |
Two-hybrid |
SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDS1 |
YAL018C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |