Standard name Systematic name Name description Description
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase Bifunctional triacylglycerol lipase and LPA acyltransferase; lipid particle-localized triacylglycerol (TAG) lipase involved in triacylglycerol mobilization; catalyzes acylation of lysophosphatidic acid (LPA); potential Cdc28p substrate; TGL5 has a paralog, TGL4, that arose from the whole genome duplication
Visualize the interactome of TGL5
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 0

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.188 0.257 0.195
Mito 0.591 0.611 0.289
Nucleolus 0.182 0.126 0.055
Peroxisome 0.330 0.192 0.172
SpindlePole 0.267 0.174 0.547
Cytoplasm NaN NaN 0.062

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TGL5 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_3282 (TAG lipase (1-16:0, 2-18:1, 3-18:0), lipid particle), r_3287 (TAG lipase (1-16:1, 2-18:1, 3-18:1), lipid particle), r_2341 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle), r_3268 (TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle), r_3292 (TAG lipase (1-18:1, 2-18:1, 3-16:0), lipid particle), r_3273 (TAG lipase (1-18:0, 2-16:1, 3-16:1), lipid particle), r_3278 (TAG lipase (1-18:1, 2-16:1, 3-18:0), lipid particle), r_3283 (TAG lipase (1-16:0, 2-18:1, 3-18:1), lipid particle), r_3264 (TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle), r_2342 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle), r_3288 (TAG lipase (1-18:0, 2-18:1, 3-16:0), lipid particle), r_3269 (TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle), r_3293 (TAG lipase (1-18:1, 2-18:1, 3-16:1), lipid particle), r_3274 (TAG lipase (1-18:0, 2-16:1, 3-18:0), lipid particle), r_3279 (TAG lipase (1-18:1, 2-16:1, 3-18:1), lipid particle), r_3284 (TAG lipase (1-16:1, 2-18:1, 3-16:0), lipid particle), r_2343 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle), r_3265 (TAG lipase (1-16:0, 2-16:1, 3-16:1), lipid particle), r_3289 (TAG lipase (1-18:0, 2-18:1, 3-16:1), lipid particle), r_3270 (TAG lipase (1-16:1, 2-16:1, 3-18:0), lipid particle), r_3294 (TAG lipase (1-18:1, 2-18:1, 3-18:0), lipid particle), r_3277 (TAG lipase (1-18:1, 2-16:1, 3-16:1), lipid particle), r_3275 (TAG lipase (1-18:0, 2-16:1, 3-18:1), lipid particle), r_3280 (TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle), r_3285 (TAG lipase (1-16:1, 2-18:1, 3-16:1), lipid particle), r_3266 (TAG lipase (1-16:0, 2-16:1, 3-18:0), lipid particle), r_3290 (TAG lipase (1-18:0, 2-18:1, 3-18:0), lipid particle), r_3271 (TAG lipase (1-16:1, 2-16:1, 3-18:1), lipid particle), r_3295 (TAG lipase (1-18:1, 2-18:1, 3-18:1), lipid particle), r_3276 (TAG lipase (1-18:1, 2-16:1, 3-16:0), lipid particle), r_3281 (TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle), r_3286 (TAG lipase (1-16:1, 2-18:1, 3-18:0), lipid particle), r_3291 (TAG lipase (1-18:0, 2-18:1, 3-18:1), lipid particle), r_2340 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle), r_3267 (TAG lipase (1-16:0, 2-16:1, 3-18:1), lipid particle), r_3272 (TAG lipase (1-18:0, 2-16:1, 3-16:0), lipid particle)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 1 2 Biochemical Activity, Biochemical Activity
TPM2 YIL138C Minor isoform of tropomyosin genetic 2 1 2 Negative Genetic, Negative Genetic
YKR075C YKR075C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 PCA
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Two-hybrid
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MHT1 YLL062C S-methylmethionine-homocysteine methyltransferase physical 1 1 1 PCA
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
HFM1 YGL251C Meiosis specific DNA helicase genetic 1 1 1 Negative Genetic
SPO74 YGL170C Component of the meiotic outer plaque of the spindle pole body genetic 1 1 1 Negative Genetic
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein physical 1 1 1 Affinity Capture-MS
HXK1 YFR053C Hexokinase isoenzyme 1 physical 1 1 1 Affinity Capture-MS
GLO2 YDR272W Cytoplasmic glyoxalase II physical 1 1 1 Affinity Capture-MS
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 1 1 1 PCA
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase physical 1 1 1 PCA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Positive Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
YLR012C YLR012C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
DGA1 YOR245C Diacylglycerol acyltransferase genetic 1 1 1 Phenotypic Enhancement
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase physical 1 1 1 PCA
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
SHC1 YER096W Sporulation-specific activator of Chs3p (chitin synthase III) genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic