Standard name Systematic name Name description Description
HFM1 YGL251C Meiosis specific DNA helicase Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
Visualize the interactome of HFM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HFM1 0 3 0 0 1

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis physical 5 4 2 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination physical 5 4 2 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Phenotypic Suppression, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
HIR1 YBL008W Subunit of the HIR complex genetic 2 1 2 Negative Genetic, Negative Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 2 1 2 Negative Genetic, Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DAL82 YNL314W Positive regulator of allophanate inducible genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest physical 1 1 1 Affinity Capture-MS
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Dosage Rescue
LSM6 YDR378C Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 1 1 1 Two-hybrid
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator physical 1 1 1 PCA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Affinity Capture-MS
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase physical 1 1 1 Affinity Capture-MS
OXP1 YKL215C 5-oxoprolinase physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
REC107 YJR021C Protein involved in early stages of meiotic recombination genetic 1 1 1 Dosage Rescue
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Positive Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Dosage Rescue
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Phenotypic Suppression
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Phenotypic Suppression
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Dosage Rescue
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase genetic 1 1 1 Negative Genetic
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 1 1 1 Synthetic Lethality
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
GAT2 YMR136W Protein containing GATA family zinc finger motifs physical 1 1 1 Affinity Capture-MS
DOT5 YIL010W Nuclear thiol peroxidase physical 1 1 1 Affinity Capture-MS