Standard name Systematic name Name description Description
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
Visualize the interactome of GRX1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.982 0.987 0.992

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 3030

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GRX1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0483 (glutathione peridoxase), r_0481 (glutathione oxidoreductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GRX2 YDR513W Cytoplasmic glutaredoxin genetic 3 3 3 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Positive Genetic, Positive Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 2 2 1 DNA to cDNA expression microarray evidence, quantitative polymerase chain reaction evidence
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 2 2 1 Affinity Capture-Western, PCA
PDE1 YGL248W Low-affinity cyclic AMP phosphodiesterase genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 2 1 1 PCA, PCA
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 PCA
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Reconstituted Complex
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Dosage Rescue
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Positive Genetic
SEN15 YMR059W Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
PTK1 YKL198C Putative serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Reconstituted Complex
YPK1 YKL126W S/T protein kinase physical 1 1 1 Reconstituted Complex
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Two-hybrid
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Synthetic Lethality
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Synthetic Lethality
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Phenotypic Enhancement
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 1 1 1 Phenotypic Enhancement
GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin genetic 1 1 1 Synthetic Rescue
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Synthetic Rescue
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Positive Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Positive Genetic
NRT1 YOR071C High-affinity nicotinamide riboside transporter genetic 1 1 1 Positive Genetic
JEN1 YKL217W Monocarboxylate/proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Reconstituted Complex
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality