Standard name Systematic name Name description Description
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
Visualize the interactome of COS4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1 225

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.562 0.638 0.548
Mito 0.051 NaN 0.181
Nucleus 0.090 0.060 0.106
Vac/Vac Memb 0.371 0.319 0.316

GFP localization & abundance

GFP localization GFP abundance
vacuole technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COS4 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
CDC73 YLR418C Component of the Paf1p complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPN1 YPR133C Protein involved in RNA polymerase II transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase physical 1 1 1 PCA
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 PCA
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 PCA
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 PCA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis physical 1 1 1 PCA
ERS1 YCR075C Protein involved in cystine transport physical 1 1 1 PCA
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p physical 1 1 1 PCA
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 PCA
HIP1 YGR191W High-affinity histidine permease physical 1 1 1 PCA
SNL1 YIL016W Ribosome-associated protein physical 1 1 1 PCA
YHC3 YJL059W Protein required for the ATP-dependent transport of arginine physical 1 1 1 PCA
PRM10 YJL108C Pheromone-regulated protein physical 1 1 1 PCA
SMF3 YLR034C Putative divalent metal ion transporter involved in iron homeostasis physical 1 1 1 PCA
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine physical 1 1 1 PCA
ELO3 YLR372W Elongase physical 1 1 1 PCA
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 PCA
FMP42 YMR221C Putative protein of unknown function physical 1 1 1 PCA
FKS3 YMR306W Protein involved in spore wall assembly physical 1 1 1 PCA
NRT1 YOR071C High-affinity nicotinamide riboside transporter physical 1 1 1 PCA
ECM3 YOR092W Non-essential protein of unknown function physical 1 1 1 PCA
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Reconstituted Complex
ATG15 YCR068W Phospholipase physical 1 1 1 PCA
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Synthetic Rescue
AQY1 YPR192W Spore-specific water channel physical 1 1 1 PCA
ATX2 YOR079C Golgi membrane protein involved in manganese homeostasis physical 1 1 1 PCA