SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
10 |
5 |
9 |
Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
3 |
3 |
2 |
Biochemical Activity, Affinity Capture-Western, Two-hybrid |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
SPO14 |
YKR031C |
Phospholipase D |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Phenotypic Suppression |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
EKI1 |
YDR147W |
Ethanolamine kinase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM11 |
YMR139W |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
physical |
1 |
1 |
1 |
Two-hybrid |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THR1 |
YHR025W |
Homoserine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR089W |
YPR089W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSR1 |
YLR380W |
Phosphatidylinositol transfer protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SFH5 |
YJL145W |
Unusual phosphatidylinositol transfer protein (PITP) that binds heme |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
POS5 |
YPL188W |
Mitochondrial NADH kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP1 |
YDR007W |
Phosphoribosylanthranilate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTD1 |
YKR080W |
NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGT1 |
YKL038W |
Glucose-responsive transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
COM2 |
YER130C |
Transcription factor that binds IME1 Upstream Activation Signal (UAS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEP4 |
YHR100C |
Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP43 |
YCR035C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Negative Genetic |