Standard name Systematic name Name description Description
POP6 YGR030C Subunit of RNase MRP, nuclear RNase P and telomerase Subunit of RNase MRP, nuclear RNase P and telomerase; forms a soluble heterodimer with Pop7p that binds P3 domain of RNase MRP and RNase P RNAs; RNase MRP cleaves pre-rRNA, nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs, while telomerase replenishes telomeric DNA; relocalizes to the cytosol in response to hypoxia
Visualize the interactome of POP6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.96 0.923 0.936
Mito NaN NaN 0.214

GFP localization & abundance

GFP localization GFP abundance
nucleus 3180

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
POP6 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase physical 6 5 5 Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Co-crystal Structure
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes physical 6 4 4 Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P physical 4 3 3 Two-hybrid, Two-hybrid, Affinity Capture-MS, Co-purification
RMP1 YLR145W Subunit of RNase MRP physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P physical 2 2 2 Two-hybrid, Affinity Capture-Western
RPR2 YIR015W Subunit of nuclear RNase P physical 2 2 2 Two-hybrid, Affinity Capture-Western
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit physical 1 1 1 Two-hybrid
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Affinity Capture-Western
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Positive Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
RNH70 YGR276C 3'-5' exoribonuclease genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme physical 1 1 1 Affinity Capture-Western