Standard name Systematic name Name description Description
YSH1 YLR277C Endoribonuclease Endoribonuclease; subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs; protein abundance increases in response to DNA replication stress; YSH1 has a paralog, SYC1, that arose from the whole genome duplication
Visualize the interactome of YSH1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.062 NaN 0.051
Nucleolus 0.118 0.057 NaN
Nucleus 0.910 0.895 0.926
Mito NaN 0.096 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleus 17400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YSH1 6 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PTA1 YAL043C Subunit of holo-CPF physical 13 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase physical 13 6 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-crystal Structure, Reconstituted Complex, Biochemical Activity
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 9 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PFS2 YNL317W Integral subunit of the pre-mRNA CPF complex physical 9 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PAP1 YKR002W Poly(A) polymerase physical 8 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western
REF2 YDR195W RNA-binding protein physical 8 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor physical 8 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) physical 7 3 5 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 6 3 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor physical 6 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
PCF11 YDR228C mRNA 3' end processing factor physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) physical 4 2 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 3 2 2 Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
HCA4 YJL033W DEAD box RNA helicase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) regulation 1 1 1 in vitro ubiquitination assay evidence
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase regulation 1 1 1 in vitro ubiquitination assay evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Dosage Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
TAF2 YCR042C TFIID subunit (150 kDa) physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation physical 1 1 1 Reconstituted Complex
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) physical 1 1 1 Affinity Capture-MS
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Synthetic Lethality
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
YNL208W YNL208W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Synthetic Rescue