Standard name Systematic name Name description Description
MRS3 YJL133W Iron transporter, mediates Fe2+ transport across inner mito membrane Iron transporter, mediates Fe2+ transport across inner mito membrane; mitochondrial carrier family member; active under low-iron conditions; may transport other cations; MRS3 has a paralog, MRS4, that arose from the whole genome duplication
Visualize the interactome of MRS3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm NaN 0.399 0.353
Endosome NaN 0.211 0.058
Mito NaN 0.280 0.516
Vac/Vac Memb NaN 0.199 0.068
SpindlePole NaN NaN 0.074

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 1360

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MRS3 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1179 (iron (II) transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MRS4 YKR052C Iron transporter of the mitochondrial carrier family genetic 8 3 6 Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 5 4 4 Dosage Rescue, Dosage Lethality, Dosage Rescue, Synthetic Growth Defect, Phenotypic Suppression
RIM2 YBR192W Mitochondrial pyrimidine nucleotide transporter genetic 5 3 4 Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression
PIC2 YER053C Mitochondrial copper and phosphate carrier genetic 3 3 1 Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 2 1 2 Dosage Rescue, Dosage Rescue
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DRE2 YKR071C Component of the cytosolic Fe-S protein assembly (CIA) machinery genetic 2 2 1 Synthetic Lethality, Dosage Lethality
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 2 2 1 Dosage Rescue, Synthetic Lethality
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
ACO1 YLR304C Aconitase genetic 1 1 1 Phenotypic Suppression
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
COB Q0105 Cytochrome b genetic 1 1 1 Dosage Rescue
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Dosage Lethality
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Synthetic Growth Defect
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Dosage Rescue
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention physical 1 1 1 PCA
VPS73 YGL104C Mitochondrial protein physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER genetic 1 1 1 Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
UBP5 YER144C Putative ubiquitin-specific protease genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Negative Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect