| Standard name | Systematic name | Name description | Description |
|---|---|---|---|
| IME4 | YGL192W | mRNA N6-adenosine methyltransferase | mRNA N6-adenosine methyltransferase; essential for meiosis in S288C but dispensable for meiosis in SK1, mediates N6-adenosine methylation of bulk mRNA during the induction of sporulation which includes the meiotic regulators IME1, IME2 and IME4 itself; repressed in haploids via production of antisense IME4 transcripts; transcribed in diploid cells where antisense transcription is repressed; orthologous to human METTL3 (MT-A70) |
Cell cycle phase and timing of transcription peak
| Cell cycle phase | Time (min) |
|---|---|
CYCLoPs localization & abundance
| WT1 | WT2 | WT3 |
|---|---|---|
| no data | no data | no data |
GFP localization & abundance
| GFP localization | GFP abundance |
|---|---|
| no data | no data |
GO term count
| Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
|---|---|---|---|---|---|
| IME4 | 4 | 3 | 0 | 0 | 1 |
Enzyme information
| Catalyzed reactions in Yeast8 |
|---|
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.| Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
|---|---|---|---|---|---|---|---|
| MUM2 | YBR057C | Protein essential for meiotic DNA replication and sporulation | physical | 3 | 2 | 2 | Two-hybrid, Affinity Capture-Western, Two-hybrid |
| SLZ1 | YNL196C | Sporulation-specific protein with a leucine zipper motif | physical | 2 | 2 | 1 | Affinity Capture-Western, Two-hybrid |
| FKH1 | YIL131C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| IXR1 | YKL032C | Transcriptional repressor that regulates hypoxic genes during normoxia | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| ABF1 | YKL112W | DNA binding protein with possible chromatin-reorganizing activity | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| MED4 | YOR174W | Subunit of the RNA polymerase II mediator complex | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| SIR2 | YDL042C | Conserved NAD+ dependent histone deacetylase of the Sirtuin family | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| SIR3 | YLR442C | Silencing protein | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| SIR4 | YDR227W | SIR protein involved in assembly of silent chromatin domains | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| RME1 | YGR044C | Zinc finger protein involved in control of meiosis | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| CDC11 | YJR076C | Component of the septin ring that is required for cytokinesis | genetic | 1 | 1 | 1 | Negative Genetic |
| CCT6 | YDR188W | Subunit of the cytosolic chaperonin Cct ring complex | genetic | 1 | 1 | 1 | Negative Genetic |
| HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| CAT5 | YOR125C | Protein required for ubiquinone (Coenzyme Q) biosynthesis | physical | 1 | 1 | 1 | Affinity Capture-MS |
| CDC37 | YDR168W | Essential Hsp90p co-chaperone | genetic | 1 | 1 | 1 | Negative Genetic |
| GLE1 | YDL207W | Cytoplasmic nucleoporin required for polyadenylated mRNA export | genetic | 1 | 1 | 1 | Negative Genetic |
| FAA1 | YOR317W | Long chain fatty acyl-CoA synthetase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| AFT1 | YGL071W | Transcription factor involved in iron utilization and homeostasis | genetic | 1 | 1 | 1 | Negative Genetic |
| SRS2 | YJL092W | DNA helicase and DNA-dependent ATPase | physical | 1 | 1 | 1 | Two-hybrid |
| KAR4 | YCL055W | Transcription factor required for response to pheromones | physical | 1 | 1 | 1 | Two-hybrid |
| LSM1 | YJL124C | Lsm (Like Sm) protein | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| MOG1 | YJR074W | Conserved nuclear protein that interacts with GTP-Gsp1p | physical | 1 | 1 | 1 | Affinity Capture-MS |
| SIF2 | YBR103W | WD40 repeat-containing subunit of Set3C histone deacetylase complex | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| SOD1 | YJR104C | Cytosolic copper-zinc superoxide dismutase | genetic | 1 | 1 | 1 | Positive Genetic |
| TAF1 | YGR274C | TFIID subunit, involved in RNA pol II transcription initiation | genetic | 1 | 1 | 1 | Synthetic Lethality |
| RGR1 | YLR071C | Subunit of the RNA polymerase II mediator complex | genetic | 1 | 1 | 1 | Negative Genetic |
| GPI12 | YMR281W | ER membrane protein involved in the second step of GPI anchor assembly | genetic | 1 | 1 | 1 | Negative Genetic |
| AFT2 | YPL202C | Iron-regulated transcriptional activator | genetic | 1 | 1 | 1 | Phenotypic Enhancement |