| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
2 |
2 |
2 |
Positive Genetic, Dosage Growth Defect |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG29 |
YPL166W |
Autophagy-specific protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LAF1 |
YMR102C |
Sterol-binding beta-propeller protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCO14 |
YHL018W |
Putative 4a-hydroxytetrahydrobiopterin dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML083C |
YML083C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML037C |
YML037C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPS100 |
YHR139C |
Protein required for spore wall maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| URA8 |
YJR103W |
Minor CTP synthase isozyme (see also URA7) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| THR1 |
YHR025W |
Homoserine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UBP16 |
YPL072W |
Deubiquitinating enzyme anchored to the outer mitochondrial membrane |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YOL029C |
YOL029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAN1 |
YDR143C |
Ubiquitin-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI22 |
YPR121W |
Protein with similarity to hydroxymethylpyrimidine phosphate kinases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LYS21 |
YDL131W |
Homocitrate synthase isozyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BSC2 |
YDR275W |
Protein of unknown function involved in multidrug resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO90 |
YJL198W |
Low-affinity phosphate transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ECM22 |
YLR228C |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPM1 |
YJL066C |
Mitochondrial intermembrane space protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRM7 |
YDL039C |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO10 |
YKR102W |
Member of the FLO family of cell wall flocculation proteins |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |