Standard name Systematic name Name description Description
FRE2 YKL220C Ferric reductase and cupric reductase Ferric reductase and cupric reductase; reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels
Visualize the interactome of FRE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FRE2 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4275 (Fe(II):NADP+ oxidoreductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FRE1 YLR214W Ferric reductase and cupric reductase genetic 3 2 3 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 1 1 1 Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
DCI1 YOR180C Peroxisomal protein genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Negative Genetic
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Negative Genetic
DFG10 YIL049W Probable polyprenol reductase genetic 1 1 1 Negative Genetic
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
GNP1 YDR508C Broad specificity amino acid permease physical 1 1 1 PCA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Dosage Rescue
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
GRE3 YHR104W Aldose reductase genetic 1 1 1 Negative Genetic
RSM26 YJR101W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
XPT1 YJR133W Xanthine-guanine phosphoribosyl transferase genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic