Standard name Systematic name Name description Description
CBP3 YPL215W Mitochondrial protein required for assembly of cytochrome bc1 complex Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation
Visualize the interactome of CBP3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi 0.103 0.059 NaN
Mito 0.892 0.888 0.950
Nuc Periphery 0.072 NaN 0.117
Nucleolus 0.108 NaN NaN
Vac/Vac Memb 0.134 0.138 NaN
Cell Periphery NaN 0.053 NaN

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 14200

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CBP3 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
COB Q0105 Cytochrome b physical 6 4 5 Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-RNA, Co-crystal Structure
CBP6 YBR120C Mitochondrial protein required for translation of the COB mRNA physical 4 3 3 Affinity Capture-Western, Affinity Capture-Western, Proximity Label-MS, Co-crystal Structure
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Proximity Label-MS
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex physical 3 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 2 2 2 Co-fractionation, Proximity Label-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor physical 2 1 1 Proximity Label-MS, Proximity Label-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 1 1 1 Two-hybrid
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome physical 1 1 1 Two-hybrid
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Phenotypic Suppression
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor physical 1 1 1 Affinity Capture-Western
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor physical 1 1 1 Affinity Capture-Western
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Co-fractionation
MRP51 YPL118W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Co-fractionation
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
COA1 YIL157C Mitochondrial inner membrane protein physical 1 1 1 Proximity Label-MS
COX15 YER141W Heme a synthase physical 1 1 1 Proximity Label-MS
CYT1 YOR065W Cytochrome c1 physical 1 1 1 Proximity Label-MS
FMP25 YLR077W Protein required for assembly of respiratory complex III physical 1 1 1 Proximity Label-MS
LPD1 YFL018C Dihydrolipoamide dehydrogenase physical 1 1 1 Proximity Label-MS
MCX1 YBR227C Non-proteolytic ATPase of the AAA family physical 1 1 1 Proximity Label-MS
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Proximity Label-MS
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex physical 1 1 1 Proximity Label-MS
MMF1 YIL051C Mitochondrial protein required for transamination of isoleucine physical 1 1 1 Proximity Label-MS
NAT2 YGR147C Protein of unknown function physical 1 1 1 Proximity Label-MS
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Proximity Label-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Proximity Label-MS
RDL2 YOR286W Protein with rhodanese activity physical 1 1 1 Proximity Label-MS
SAL1 YNL083W ADP/ATP transporter physical 1 1 1 Proximity Label-MS
TES1 YJR019C Peroxisomal acyl-CoA thioesterase physical 1 1 1 Proximity Label-MS
TIM50 YPL063W Essential component of the TIM23 complex physical 1 1 1 Proximity Label-MS
MRX9 YDL027C Protein that associates with mitochondrial ribosome physical 1 1 1 Proximity Label-MS
MRX19 YDL183C Protein that may form an active mitochondrial KHE system physical 1 1 1 Proximity Label-MS
MRX20 YFR045W Putative mitochondrial transport protein physical 1 1 1 Proximity Label-MS
YLF2 YHL014C Protein of unknown function physical 1 1 1 Proximity Label-MS
YME1 YPR024W Catalytic subunit of i-AAA protease complex physical 1 1 1 Proximity Label-MS
MRX15 YNR040W Membrane-associated mitoribosome receptor physical 1 1 1 Proximity Label-MS
MRX4 YPL168W Protein that associates with mitochondrial ribosome physical 1 1 1 Proximity Label-MS
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL15 YLR312W-A Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA physical 1 1 1 Proximity Label-MS
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Proximity Label-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Synthetic Growth Defect
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function physical 1 1 1 Proximity Label-MS
AIF1 YNR074C Mitochondrial cell death effector physical 1 1 1 Affinity Capture-MS
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS