| Standard name | Systematic name | Name description | Description |
|---|---|---|---|
| THI5 | YFL058W | Protein involved in synthesis of the thiamine precursor HMP | Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP |
Cell cycle phase and timing of transcription peak
| Cell cycle phase | Time (min) |
|---|---|
CYCLoPs localization & abundance
| WT1 | WT2 | WT3 |
|---|---|---|
| no data | no data | no data |
GFP localization & abundance
| GFP localization | GFP abundance |
|---|---|
| no data | no data |
GO term count
| Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
|---|---|---|---|---|---|
| THI5 | 3 | 0 | 0 | 0 | 0 |
Enzyme information
| Catalyzed reactions in Yeast8 |
|---|
| r_1603 (4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase) |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.| Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
|---|---|---|---|---|---|---|---|
| IXR1 | YKL032C | Transcriptional repressor that regulates hypoxic genes during normoxia | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| SPT10 | YJL127C | Histone H3 acetylase with a role in transcriptional regulation | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| TFC7 | YOR110W | RNA pol III transcription initiation factor complex (TFIIIC) subunit | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| SIR2 | YDL042C | Conserved NAD+ dependent histone deacetylase of the Sirtuin family | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| SIR3 | YLR442C | Silencing protein | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| SIR4 | YDR227W | SIR protein involved in assembly of silent chromatin domains | regulation | 1 | 1 | 1 | RNA-sequencing evidence |
| THI2 | YBR240C | Transcriptional activator of thiamine biosynthetic genes | regulation | 1 | 1 | 1 | northern blot evidence |
| PDC2 | YDR081C | Transcription factor for thiamine-regulated genes | regulation | 1 | 1 | 1 | northern blot evidence |
| RPO21 | YDL140C | RNA polymerase II largest subunit B220 | genetic | 1 | 1 | 1 | Negative Genetic |
| PRP19 | YLL036C | Splicing factor associated with the spliceosome | genetic | 1 | 1 | 1 | Negative Genetic |
| NOP12 | YOL041C | Nucleolar protein involved in pre-25S rRNA processing | genetic | 1 | 1 | 1 | Negative Genetic |
| CCT4 | YDL143W | Subunit of the cytosolic chaperonin Cct ring complex | genetic | 1 | 1 | 1 | Negative Genetic |
| MCD1 | YDL003W | Essential alpha-kleisin subunit of the cohesin complex | genetic | 1 | 1 | 1 | Positive Genetic |
| LEA1 | YPL213W | Component of U2 snRNP complex | genetic | 1 | 1 | 1 | Negative Genetic |
| MAF1 | YDR005C | Highly conserved negative regulator of RNA polymerase III | genetic | 1 | 1 | 1 | Negative Genetic |
| SRP54 | YPR088C | Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) | physical | 1 | 1 | 1 | Co-purification |
| SWD1 | YAR003W | Subunit of the COMPASS (Set1C) complex | genetic | 1 | 1 | 1 | Negative Genetic |
| RSP5 | YER125W | NEDD4 family E3 ubiquitin ligase | physical | 1 | 1 | 1 | Protein-peptide |
| CDC21 | YOR074C | Thymidylate synthase | genetic | 1 | 1 | 1 | Negative Genetic |
| SWC5 | YBR231C | Component of the SWR1 complex | genetic | 1 | 1 | 1 | Positive Genetic |
| ATG8 | YBL078C | Ub-like protein | genetic | 1 | 1 | 1 | Negative Genetic |
| MGR3 | YMR115W | Subunit of the mitochondrial (mt) i-AAA protease supercomplex | genetic | 1 | 1 | 1 | Negative Genetic |
| SHE1 | YBL031W | Mitotic spindle protein | genetic | 1 | 1 | 1 | Positive Genetic |
| ERG3 | YLR056W | C-5 sterol desaturase | genetic | 1 | 1 | 1 | Positive Genetic |
| NCS2 | YNL119W | Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs | genetic | 1 | 1 | 1 | Negative Genetic |
| MDM35 | YKL053C-A | Mitochondrial intermembrane space protein | genetic | 1 | 1 | 1 | Negative Genetic |
| MRM2 | YGL136C | Mitochondrial 2' O-ribose methyltransferase | genetic | 1 | 1 | 1 | Positive Genetic |
| THI5 | YFL058W | Protein involved in synthesis of the thiamine precursor HMP | physical | 1 | 1 | 1 | Co-crystal Structure |
| TIF2 | YJL138C | Translation initiation factor eIF4A | genetic | 1 | 1 | 1 | Negative Genetic |
| YAR1 | YPL239W | Nucleocytoplasmic shuttling assembly chaperone | genetic | 1 | 1 | 1 | Negative Genetic |
| YME1 | YPR024W | Catalytic subunit of i-AAA protease complex | genetic | 1 | 1 | 1 | Negative Genetic |
| UBA3 | YPR066W | Protein that activates Rub1p (NEDD8) before neddylation | genetic | 1 | 1 | 1 | Negative Genetic |